** Shares of drug developer First Wave BioPharma Inc
FWBI.O rise ~36% to $6, among top gainers across U.S.
exchanges
** Co says it has filed a U.S. Provisional Patent
application involving composition of matter improvements
designed to enhance its pancreatic disorder drug adrulipase's
delayed release profile
** Says filing adds to the intellectual property portfolio
governing the drug, including its formulation and methods of use
** First Wave expects to initiate a mid-stage trial at the
beginning of 2023 after FDA's approval for human trials
** Co is evaluating the drug as a potential treatment for a
type of pancreatic disorder associated with cystic fibrosis and
chronic pancreatitis
** Adds in vitro research indicates the enhanced formulation
has the potential to decrease the number of pills a patients
would need to take
** Stock lost ~98% last year
(Reporting by Sriparna Roy)
((Sriparna.Roy@thomsonreuters.com;))