** Shares of drug developer Gritstone bio GRTS.O jump ~27%
to $3.27, among top pct gainers across U.S. exchanges
** Set for biggest one-day pct gain in nearly 2 years
** Co says United States Patent and Trademark Office issued
two new patents related to co's self amplifying mRNA vaccine
platform technology
** One patent covers co's lead product, GRANITE, which is a
individualized cancer vaccine candidate
** The other patent covers antigen-encoding samRNA vectors
and has broad applicability across co's candidates in oncology
and infectious disease - GRTS
** Self amplifying mRNA replicates once in the cell,
creating copies of the original strand of RNA, unlike
traditional mRNA
** Despite session's gain, stock down ~75% YTD
(Reporting by Sriparna Roy)
((Sriparna.Roy@thomsonreuters.com;))