** Jefferies estimates that 4-5.5 billion COVID-19 vaccine
doses will be delivered globally this year, mostly outside the
European Union and United States, which have received the lion's
share of supplies
** The largest supply/demand gaps in are in low and
lower-middle income countries, Jefferies says, estimating that
only 2% of people in these countries received boosters last year
compared with 46% in the EU and 38% in the U.S.
** Near-term revenues from vaccine deliveries should mainly
benefit Pfizer-BioNTech PFE.N 22UAy.DE , Moderna MRNA.O and
emerging Novavax NVAX.O , adds Jefferies
** "A few potential innovations could be critical to shape
the future COVID-19 vaccine landscape," brokerage says, pointing
to potential improvements in durability, safety and convenience
as the virus evolves
** Effective and tolerated boosters, consistent efficacy
across demographics, accessible logistics and pan-respiratory
disease coverage will be some key areas of innovation, brokerage
says
** Icosavax ICVX.O is one of Jefferies' top picks for
2022, as it launches pre-clinical studies of an Omicron specific
virus-like particle-based vaccine with VBI Vaccines VBIV.O
** Broker estimates over 250 COVID-19 vaccine candidates are
undergoing trials across the world, developed by firms such as
AstraZeneca AZN.L , Sanofi SASY.PA , Valneva VLS.PA , Ocugen
OCGN.O and GSK/Medicago GSK.L
(Reporting by Sarah Morland)
((sarah.morland@tr.com
mailto:sarah.morland@thomsonreuters.com))