Updates
** Shares of Immutep IMM.AX drop as much as 92.9% to a lifetime low of A$0.028
** Stock logs its largest intraday pct drop
** IMM trading 88.1% lower at 4.7 Australian cents a share, as of 0400 GMT
** Australian biotechnology firm says an independent data monitoring committee for its TACTI-004 Phase III study for treatment of non-small cell lung cancer has recommended discontinuation of trial
** Says recommendation following a planned interim futility analysis
** Adds enrolment in the study to be halted, co to implement an orderly wind-down of the study
** More than 379.3 million shares change hands, over 142 times the 30-day average
** Jefferies downgrades IMM to "hold" from "buy", cuts PT to 4 cents from A$2.20
** Brokerage calls it a "surprising outcome", says its valuation was based on one product, the efficacy of which is now in question
** Stock down 89.2% YTD
(Reporting by Nikita Maria Jino and Sameer Manekar in Bengaluru)
((Nikita.Jino@thomsonreuters.com))