Inspire Medical Systems dips as Jefferies cuts to 'hold'

Inspire Medical Systems

24/10/2025 13:33

** Shares of medtech company Inspire Medical Systems INSP.N fall nearly 3% to $77.9 in premarket

** Jefferies downgrades stock rating to "hold" from "buy"

*  Cites reduced confidence in co’s ability to accelerate sales growth to medium-term targets, and no longer expects valuation upside from multiple expansion.

** Brokerage also slashes PT to $85 from $160, a 6% upside to the stock's last close

** Jefferies says ongoing headwinds from GLP-1 weight-loss drugs, rising competition and market share losses, weak physician reimbursement, and limited expectations for Inspire 5 (co’s next-generation sleep apnea device) are likely to hinder sales growth acceleration in 2026

** Average rating of 20 analysts is "buy"; median PT $125 - data compiled by LSEG

** As of last close, co down nearly 57% YTD

 (Reporting by Akriti Shah in Bengaluru)

 ((akriti.shah@thomsonreuters.com))