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Publication of Scheme Document

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RNS Number : 5736N  Instem plc  25 September 2023

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR
INDIRECTLY, IN, INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE
A VIOLATION OF THE RELEVANT LAWS OR REGULATIONS OF SUCH JURISDICTION

FOR IMMEDIATE RELEASE

( )

25 September 2023

RECOMMENDED CASH OFFER

by

ICHOR MANAGEMENT LIMITED

(a newly incorporated company controlled by funds managed by ARCHIMED SAS)

for

INSTEM PLC

to be effected by means of a Scheme of Arrangement

under Part 26 of the Companies Act 2006

Publication of Scheme Document

 

On 30 August 2023, the board of directors of Ichor Management Limited
("Bidco") and the board of directors of Instem plc ("Instem") announced that
they had reached agreement on the terms of a recommended cash offer by Bidco
for the entire issued and to be issued share capital of Instem.

The board of Instem is now providing the following update on the Acquisition,
which will be implemented by means of a Court-sanctioned scheme of arrangement
between Instem and relevant Instem shareholders under Part 26 of the Companies
Act 2006 (the "Scheme").

Capitalised terms used in this announcement shall, unless otherwise defined,
have the meanings set out in Part 8 of the Scheme Document (as defined below).

Publication and posting of the Scheme Document

The board of Instem is pleased to announce that it has today published a
circular in relation to the Scheme (the "Scheme Document"), together with the
Forms of Proxy for the Court Meeting and the General Meeting. The Scheme
Document sets out, amongst other things, a letter from the Chairman of Instem,
the full terms and conditions of the Scheme, an explanatory statement pursuant
to section 897 of the Companies Act 2006, an expected timetable of principal
events, notices of the Court Meeting and General Meeting and details of the
actions to be taken by Instem Shareholders.

Hard copies of the Scheme Document and Forms of Proxy for the Court Meeting
and the General Meeting are being posted today to Instem Shareholders and, for
information only, to persons with information rights. Instem will also be
sending details of the proposals being made to holders of the Awards. Copies
of the Scheme Document and Forms of Proxy will also be made available on
Instem's website at https://investors.instem.com
(https://investors.instem.com) and Bidco's website at www.Ichor-offer.com
(http://www.Ichor-offer.com) later today.

Notices of the Court Meeting and General Meeting

As further detailed in the Scheme Document, to become Effective, the Scheme
requires, among other things, that the requisite majority of Scheme
Shareholders vote in favour of the Scheme at the Court Meeting (or any
adjournment of the Court Meeting) and that the requisite majority of Instem
Shareholders vote in favour of the Special Resolution to be proposed at the
General Meeting. The Scheme is also subject to the satisfaction or (where
applicable) waiver of the Conditions and further terms set out in the Scheme
Document, including (amongst other things) the NSIA Condition. The Scheme must
also be sanctioned by the Court.

Notices convening the Court Meeting and the General Meeting, each of which
will be held at the offices of Squire Patton Boggs (UK) LLP, No 1
Spinningfields, 1 Hardman Square, Manchester, M3 3EB, are set out in the
Scheme Document. The Court Meeting will start at 10.00 a.m. on 19 October 2023
(London time) and the General Meeting at 10.15 a.m. on 19 October 2023 (London
time) (or as soon as reasonably practicable thereafter as the Court Meeting
shall have been concluded or adjourned). Forms of Proxy for use at such
meetings will be enclosed with the Scheme Document. ). Any changes to the
arrangements for the Court Meeting and the General Meeting will be
communicated to Scheme Shareholders and Instem Shareholders before the
relevant meeting through Instem's website at https://investors.instem.com
(https://investors.instem.com) and Bidco's website at www.Ichor-offer.com
(http://www.Ichor-offer.com) , and by announcement through a Regulatory
Information Service.

It is important that, for the Court Meeting in particular, as many votes as
possible are cast so that the Court may be satisfied that there is a fair
representation of the opinion of Scheme Shareholders. Scheme Shareholders are
therefore strongly urged to complete and return their Forms of Proxy, or to
appoint a proxy through CREST or electronically as soon as possible. Doing so
will not prevent you from attending, speaking and voting in person at the
Meetings if you wish and are entitled to do so.

Scheme Shareholders should read the Scheme Document in its entirety before
making a decision in respect of the Scheme.

Recommendation

The Instem Directors, who have been so advised by Rothschild & Co and
Singer Capital Markets as to the financial terms of the Acquisition, consider
the terms of the Acquisition to be fair and reasonable. In providing advice to
the Instem Directors, Rothschild & Co and Singer Capital Markets have
taken into account the commercial assessments of the Instem Directors.
Rothschild & Co and Singer Capital Markets are jointly providing
independent financial advice to the Instem Directors for the purposes of Rule
3 of the Code. Singer Capital Markets is also the Company's nominated adviser.

Accordingly, in order to implement the Acquisition, the Instem Directors
recommend unanimously that Instem Shareholders vote to approve the Scheme at
the Court Meeting and vote in favour of the Special Resolution at the General
Meeting as those Instem Directors who hold a beneficial interest in Instem
Shares have irrevocably undertaken to do (or procure to be done) in respect of
their own (and their connected persons') beneficial holdings of Instem Shares
(in a personal capacity or through a nominee or related family trust).

Instem share plans

The Scheme will apply to any Instem Shares which are unconditionally allotted,
issued, or transferred before the Scheme Record Time to satisfy the vesting
and/or exercise of outstanding awards over Instem Shares under the Instem
Share Plans.

It is proposed to amend the Instem Articles at the General Meeting to provide
that, if the Scheme becomes Effective, any Instem Shares issued to any person
other than Bidco and/or its nominees after the Scheme Record Time (including
in satisfaction of the exercise or vesting of Awards under the Instem Share
Plans) will be automatically transferred to, or to the order of, Bidco on the
same terms as the Scheme Shareholders under the Scheme in exchange for the
provision by Bidco of the same consideration payable per Instem Share under
the Scheme. Further information in respect of the proposed amendments to the
Instem Articles is contained in paragraph 10.3 of Part 2 of the Scheme
Document and in the Notice of General Meeting at Part 10

Delisting and cancellation of admission to trading of Instem Shares

Before the Scheme becomes Effective, it is intended that an application will
be made to the London Stock Exchange for the cancellation of trading of the
Instem Shares on AIM, to take effect shortly after the Effective Date. The
last day of dealings in, and registration of transfers of, Instem Shares on
AIM is expected to be the Business Day immediately after the Sanction Hearing.

On the Effective Date, share certificates in respect of Instem Shares will
cease to be valid and entitlements to Instem Shares held within the CREST
system will be cancelled. Instem Shareholders shall be required to return
share certificates to Instem or destroy them following the Effective Date.

It is intended that, following the Effective Date and after its shares are
delisted, Instem will be re-registered as a private limited company under the
relevant provisions of the Companies Act.

 

Timetable

The Scheme Document contains an expected timetable of principal events
relating to the Scheme, which is also set out in the Appendix to this
announcement. The Scheme remains conditional on the approval of Scheme
Shareholders at the Court Meeting and of Instem Shareholders of the Special
Resolution to be proposed at the General Meeting and to the satisfaction or
waiver of the other Conditions set out in the Scheme Document. The Scheme is
expected to become Effective two Business Days after the Court Hearing. Any
update to the expected timetable will be announced by Instem through a
Regulatory Information Service, with such announcement being made available on
Instem's website at https://investors.instem.com
(https://investors.instem.com) and Bidco's website at www.Ichor-offer.com
(http://www.Ichor-offer.com) .

Shareholder helpline

If you have any questions relating to the Scheme Document, the Court Meeting
or the General Meeting or the completion and return of your Forms of Proxy,
please contact the Shareholder Helpline operated by Computershare by calling
0370 703 6041 (or +44 (0)370 703 6041 if calling from outside the UK). Calls
are charged at the standard geographic rate and will vary by provider. Calls
from outside the United Kingdom will be charged at the applicable
international rate. The Shareholder Helpline is open between 8.30 a.m. and
5.30 p.m., Monday to Friday (excluding public holidays in England and Wales).
Different charges may apply to calls from mobile telephones and calls may be
recorded and randomly monitored for security and training purposes. Please
note the Shareholder Helpline cannot provide advice on the merits of the
Acquisition or the Scheme nor give any financial, investment, legal or tax
advice.

 

Instem

Phil
Reason
Via Walbrook

Nigel Goldsmith

Rothschild & Co (Financial Adviser to Instem)

Alistair
Allen
Tel: +44 (0) 161 827 3800

Julian Hudson

Tom Palmer

 

Singer Capital Markets Advisory LLP (Nominated Adviser, Joint Financial
Adviser and Joint Broker to Instem)

Peter
Steel
Tel: +44 (0) 20 7496 3000

Alex Bond

Oliver Platts

Stifel Nicolaus Europe Limited (Joint Broker to Instem)

Ben
Maddison
Tel: +44 (0) 20 7710 7600

Richard Short

 

Walbrook Financial PR (Public Relations Adviser to Instem)

Tom
Cooper
Tel: +44 (0) 20 7933 8780

Nick Rome

Joe Walker

 

ARCHIMED SAS

Vincent
Guillaumot
Tel: +33 4 81 11 35 33

Brian Sheridan

Sandrine Laporte

 

Moelis & Company UK LLP (Financial Adviser to ARCHIMED and Bidco)

Philippe Gallone
 
Tel: +44 (0) 20 7634 3500

Chris Raff

François Saint-Lo

Simon Chaudhuri

 

Latham & Watkins (London) LLP are retained as legal adviser to ARCHIMED
and Bidco.

Squire Patton Boggs (UK) LLP are retained as legal adviser to Instem.

Disclaimers

Rothschild & Co, which is authorised and regulated by the FCA in the
United Kingdom, is acting exclusively as joint financial adviser to Instem and
for no one else in connection with the matters referred to in this
Announcement and will not be responsible to anyone other than Instem for
providing the protections afforded to clients of Rothschild & Co, nor for
providing advice in relation to the acquisition of Instem or any other matters
referred to in this Announcement. Neither Rothschild & Co nor any of its
subsidiaries, branches or affiliates (nor their respective directors,
officers, employees or agents) owes or accepts any duty, liability or
responsibility whatsoever (whether direct or indirect, whether in contract, in
tort, under statute or otherwise) to any person who is not a client of
Rothschild & Co in connection with this Announcement, any statement
contained in this Announcement, the acquisition of Instem or otherwise. No
representation or warranty, express or implied, is made by Rothschild & Co
as to the contents of this Announcement.

Singer Capital Markets, which is authorised and regulated by the FCA in the
United Kingdom, is acting exclusively as joint financial adviser and nominated
adviser to Instem and no one else in connection with the matters referred to
in this Announcement and will not be responsible to anyone other than Instem
for providing the protections afforded to clients of Singer Capital Markets,
nor for providing advice in relation to the acquisition of Instem or any other
matters referred to in this Announcement. Neither Singer Capital Markets nor
any of its affiliates (nor their respective directors, partners, officers,
employees or agents) owes or accepts any duty, liability or responsibility
whatsoever (whether direct or indirect, whether in contract, in tort, under
statute or otherwise) to any person who is not a client of Singer Capital
Markets in connection with this Announcement, any statement contained in this
Announcement, the acquisition of Instem or otherwise. No representation or
warranty, express or implied, is made by Singer Capital Markets as to the
contents of this Announcement.

Moelis, which is authorised and regulated by the FCA in the United Kingdom, is
acting exclusively for ARCHIMED and Bidco and no one else in connection with
the matters referred to in this Announcement and will not be responsible to
anyone other than ARCHIMED and Bidco for providing the protections afforded to
clients of Moelis, nor for providing advice in relation to the acquisition of
Instem or any other matters referred to in this Announcement. Neither Moelis
nor any of its affiliates (nor their respective directors, officers, employees
or agents) owes or accepts any duty, liability or responsibility whatsoever
(whether direct or indirect, whether in contract, in tort, under statute or
otherwise) to any person who is not a client of Moelis in connection with this
Announcement, any statement contained in this Announcement, the acquisition of
Instem or otherwise.

Further information

This Announcement is for information purposes only and is not intended to and
does not constitute, or form any part of, an offer to sell or subscribe for or
any invitation to purchase or subscribe for any securities or the solicitation
of any vote or approval in any jurisdiction pursuant to the Acquisition or
otherwise. The Acquisition will be made solely through and on the terms set
out in the Scheme Document (or, in the event that the Acquisition is to be
implemented by means of a Takeover Offer, the Offer Document) and the
accompanying Forms of Proxy, which contain the full terms and conditions of
the Acquisition, including details of how to vote in respect of the
Acquisition. Any vote, approval, decision or other response to the Acquisition
should be made only on the basis of the information in the Scheme Document
(or, if the Acquisition is implemented by way of a Takeover Offer, the Offer
Document). Scheme Shareholders are strongly advised to read the formal
documentation in relation to the Acquisition once it has been despatched.

This Announcement does not constitute a prospectus or prospectus exempted
document.

The statements contained in this Announcement are made as at the date of this
Announcement, unless some other time is specified in relation to them, and
service of this Announcement shall not give rise to any implication that there
has been no change in the facts set forth in this Announcement since such
date.

Overseas shareholders

This Announcement has been prepared for the purpose of complying with English
law, the AIM Rules and the Code and the information disclosed may not be the
same as that which would have been disclosed if this Announcement had been
prepared in accordance with the laws of jurisdictions outside the United
Kingdom.

The laws of the relevant jurisdictions may affect the availability of the
Acquisition to persons who are not resident in the United Kingdom. Persons who
are not resident in the United Kingdom, or who are subject to laws of any
jurisdiction other than the United Kingdom, should inform themselves about,
and observe any applicable requirements. Any person (including, without
limitation, nominees, trustees and custodians) who would, or otherwise intends
to, forward this Announcement, the Scheme Document or any accompanying
document to any jurisdiction outside the United Kingdom should refrain from
doing so and seek appropriate professional advice before taking any action. In
particular, the ability of persons who are not resident in the United Kingdom
to vote their Instem Shares at the Court Meeting or the General Meeting, or to
execute and deliver Forms of Proxy appointing another to vote their Instem
Shares in respect of the Court Meeting or the General Meeting on their behalf,
may be affected by the laws of the relevant jurisdiction in which they are
located.

Any failure to comply with the applicable legal or regulatory requirements may
constitute a violation of the laws and/or regulations of any such
jurisdiction. To the fullest extent permitted by applicable law, the companies
and persons involved in the Acquisition disclaim any responsibility and
liability for the violation of such restrictions by any person.

Unless  otherwise  determined  by  Bidco  or  required  by  the
Code  and  permitted  by  applicable  law  and  regulation, the
Acquisition will not be made, directly or indirectly, in or into or by use of
the mails or any other means or instrumentality (including, without
limitation, telephonic or electronic) of interstate or foreign commerce of, or
any facility of a national, state or other securities exchange of, a
Restricted Jurisdiction, and the Acquisition will not be capable of acceptance
by any such use, means, instrumentality or facility or from within a
Restricted Jurisdiction. Accordingly, copies of this Announcement and formal
documentation relating to the Acquisition are not being, and must not be,
directly or indirectly, mailed or otherwise forwarded or distributed in, into
or from a Restricted Jurisdiction and persons receiving this Announcement
(including custodians, nominees and trustees) must not distribute or send it
into or from a Restricted Jurisdiction. In the event that the Acquisition is
implemented by way of a Takeover Offer and extended into the US, Bidco will do
so in satisfaction of the procedural and filing requirements of US securities
laws at that time, to the extent applicable thereto. The Acquisition relates
to the shares of a company incorporated in England and it is proposed to be
made by means of a scheme of arrangement provided for under English law. The
Scheme will relate to the shares of a UK company that is a "foreign private
issuer" as defined under Rule 3b-4 under the US Exchange Act. A transaction
effected by means of a scheme of arrangement is not subject to any shareholder
vote, proxy solicitation and tender offer rules under the US Exchange Act.
Accordingly, the Scheme is subject to the disclosure requirements and
practices applicable in the UK to schemes of arrangement, which differ from
the disclosure requirements and practices of US shareholder vote, proxy
solicitation or tender offer rules. Financial information included in the
relevant documentation will have been prepared in accordance with accounting
standards applicable in the UK and may not be comparable to the financial
information of, or the accounting standards applicable to, US companies.
However, if Bidco were to elect to implement the Acquisition by means of a
Takeover Offer, such Takeover Offer shall be made in compliance with all
applicable laws and regulations, including section 14(e) of the US Exchange
Act and Regulation 14E thereunder, if applicable. Such Takeover Offer would be
made in the US by Bidco and no one else. In addition to any such Takeover
Offer, Bidco, certain affiliated companies and the nominees or brokers (acting
as agents) may make certain purchases of, or arrangements to purchase, shares
in Instem outside such Takeover Offer during the period in which such Takeover
Offer would remain open for acceptance. If such purchases or arrangements to
purchase are made they would be made outside the United States in compliance
with applicable law, including the US Exchange Act. It may be difficult for a
US-based investor to enforce his or her rights and any claim he or she may
have arising under US securities laws, since the Scheme relates to the shares
of a company located in the UK, and some or all of its officers and directors
may be residents of non-US jurisdictions. A US-based investor may not be able
to sue a company located in the UK, or its officers or directors, in a foreign
court for alleged violations of US securities laws, and it may be difficult to
compel a foreign company and its affiliates to subject themselves to a US
court's judgment.

 

Forward-looking statements

This Announcement, oral statements made regarding the Acquisition, and other
information published by Instem, Bidco and ARCHIMED may contain certain
"forward-looking statements" with respect to Instem, Bidco and ARCHIMED. These
forward-looking statements can be identified by the fact that they do not
relate only to historical or current facts. Forward-looking statements often
use words such as "anticipate", "target", "expect", "estimate", "intend",
"plan", "goal", "believe", "will", "may", "should", "would", "could" or other
words or terms of similar meaning or the negative thereof. Forward-looking
statements include, for example, statements relating to the following: (i)
future capital expenditures, expenses, revenues, earnings, synergies, economic
performance, indebtedness, financial condition, dividend policy, losses and
future prospects; (ii) business and management strategies of ARCHIMED and/or
Bidco and the expansion and growth of Instem and potential synergies resulting
from the Acquisition; and (iii) the effects of government regulation on the
business of Instem.

These forward-looking statements involve known and unknown risks,
uncertainties and other factors which may cause actual results, performance or
developments to differ materially from those expressed in or implied by such
forward-looking statements. These forward-looking statements are based on
numerous assumptions regarding present and future strategies and environments.
None of ARCHIMED, Bidco or Instem, nor any of their respective associates,
directors, officers, employees or advisers, provides any representation,
assurance or guarantee that the occurrence of the events expressed or implied
in any forward-looking statements in this Announcement will actually occur.
You are cautioned not to place undue reliance on such forward-looking
statements, which speak only as of the date hereof. All subsequent oral or
written forward-looking statements attributable to ARCHIMED, Bidco or Instem
or any person acting on their behalf are expressly qualified in their entirety
by the cautionary statement above. Should one or more of these risks or
uncertainties materialise, or should underlying assumptions prove incorrect,
actual results may vary materially from those described in this Announcement.
None of ARCHIMED, Bidco or Instem assume any obligation to update publicly or
revise forward-looking or other statements contained in this Announcement,
whether as a result of new information, future events or otherwise, except to
the extent legally required.

No profit forecasts, estimates or qualified benefits statements

No statement in this Announcement is intended as a profit forecast or estimate
for ARCHIMED, Bidco or Instem in respect of any period and no statement in
this Announcement should be interpreted to mean that earnings or earnings per
Instem Share for the current or future financial years would necessarily match
or exceed the historical published earnings or earnings per Instem Share.

Right to switch to a Takeover Offer

Subject to the terms of the Co-operation Agreement, Bidco reserves the right
to elect, with the consent of the Takeover Panel, to implement the Acquisition
by way of a Takeover Offer for the entire issued and to be issued ordinary
share capital of Instem as an alternative to the Scheme. In such an event, the
Takeover Offer will be made in accordance with the terms and conditions set
out in this Announcement which would apply to the Scheme (with any
modifications or amendments to such terms and conditions as may be required by
the Takeover Panel or which are necessary as a result of Bidco's election to
implement the Acquisition by way of a Takeover Offer), in accordance with the
Co-operation Agreement and subject to the amendment referred to in Appendix I
to this Announcement.

Publication on website

In accordance with Rule 26.1 of the Code, a copy of this Announcement will be
made available (subject to certain restrictions relating to persons resident
in Restricted Jurisdictions), free of charge, on Instem's website at
https://investors.instem.com and on Bidco's website at www.Ichor-offer.com by
no later than 12:00 noon on the Business Day following the date of this
Announcement. Neither the contents of this website nor the content of any
other website accessible from hyperlinks on such websites is incorporated
into, or forms part of, this Announcement.

Requesting hard copies

In accordance with Rule 30.3 of the Code, a person so entitled may request a
hard copy of this Announcement, free of charge, by contacting Instem's
registrar, Computershare Investor Services PLC during business hours (8.30
a.m. to 5.30 p.m.) on +44 (0)370 703 6041 or by submitting a request in
writing to Computershare Investor Services PLC at The Pavilions, Bridgwater
Road, Bristol, BS13 8AE. For persons who receive a copy of this Announcement
in electronic form or via a website notification, a hard copy of this
Announcement will not be sent unless so requested. In accordance with Rule
30.3 of the Code, a person so entitled may also request that all future
documents, announcements and information to be sent to them in relation to the
Acquisition should be in hard copy form.

 

Electronic communications - information for Instem Shareholders

Please be aware that addresses, electronic addresses and certain information
provided by Instem Shareholders, persons with information rights and other
relevant persons for the receipt of communications from Instem may be provided
to Bidco during the Offer Period as required under section 4 of Appendix 4 of
the Code to comply with Rule 2.11(c) of the Code.

Rounding

Certain figures included in this Announcement have been subjected to rounding
adjustments. Accordingly, figures shown for the same category presented in
different tables may vary slightly and figures shown as totals in certain
tables may not be an arithmetic aggregation of the figures that precede them.

Disclosure requirements of the Code

Under Rule 8.3(a) of the Code, any person who is interested in 1 per cent. or
more of any class of relevant securities of Instem or of any securities
exchange offeror (being any offeror other than an offeror in respect of which
it has been announced that its offer is, or is likely to be, solely in cash)
must make an Opening Position Disclosure following the commencement of the
Offer Period and, if later, following the announcement in which any securities
exchange offeror is first identified. An Opening Position Disclosure must
contain details of the person's interests and short positions in, and rights
to subscribe for, any relevant securities of each of: (i) Instem and (ii) any
securities exchange offeror(s). An Opening Position Disclosure by a person to
whom Rule 8.3(a) applies must be made by no later than 3.30 p.m. (London time)
on the 10th Business Day following the commencement of the Offer Period and,
if appropriate, by no later than 3.30 p.m. (London time) on the 10th Business
Day following the announcement in which any securities exchange offeror is
first identified. Relevant persons who deal in the relevant securities of
Instem or of a securities exchange offeror prior to the deadline for making an
Opening Position Disclosure must instead make a Dealing Disclosure.

Under Rule 8.3(b) of the Code, any person who is, or becomes, interested in 1
per cent. or more of any class of relevant securities of Instem or of any
securities exchange offeror must make a Dealing Disclosure if the person deals
in any relevant securities of Instem or of any securities exchange offeror. A
Dealing Disclosure must contain details of the dealing concerned and of the
person's interests and short positions in, and rights to subscribe for, any
relevant securities of each of (i) Instem and (ii) any securities exchange
offeror, save to the extent that these details have previously been disclosed
under Rule 8. A Dealing Disclosure by a person to whom Rule 8.3(b) applies
must be made by no later than 3.30 p.m. (London time) on the Business Day
following the date of the relevant dealing.

If two or more persons act together pursuant to an agreement or understanding,
whether formal or informal, to acquire or control an interest in relevant
securities of Instem or a securities exchange offeror, they will be deemed to
be a single person for the purpose of Rule 8.3.

Opening Position Disclosures must also be made by Instem and by any offeror,
and Dealing Disclosures must also be made by Instem, by any offeror and by any
persons acting in concert with any of them (see Rules 8.1, 8.2 and 8.4).

Details of the offeree and offeror companies in respect of whose relevant
securities Opening Position Disclosures and Dealing Disclosures must be made
can be found in the Disclosure Table on the Takeover Panel's website at
www.thetakeoverpanel.org.uk (http://www.thetakeoverpanel.org.uk) , including
details of the number of relevant securities in issue, when the Offer Period
commenced and when any offeror was first identified. You should contact the
Takeover Panel's Market Surveillance Unit on +44 (0) 20 7638 0129 if you are
in any doubt as to whether you are required to make an Opening Position
Disclosure or a Dealing Disclosure.

General

If you are in any doubt about the contents of this Announcement or the action
you should take, you are recommended to seek your own independent financial
advice immediately from your stockbroker, bank manager, solicitor or
independent financial adviser duly authorised under FSMA if you are resident
in the United Kingdom or, if not, from another appropriate authorised
independent financial adviser.

 

Appendix

Expected Timetable of Principal Events

 

 Event                                                                     Time and/or date
 Publication of the Scheme Document                                        25 September 2023
 Latest time for lodging Forms of Proxy for the:
             Court Meeting (BLUE form)                                     10.00 a.m. on 17 October 2023¹
             General Meeting (WHITE form)                                  10.15 a.m. on 17 October 2023²
 Voting Record Time                                                        6.00 p.m. on 17 October 2023³
 Court Meeting                                                             10.00 a.m. on 19 October 2023
 General Meeting                                                           10.15 a.m. on 19 October 2023⁴
 The following dates are indicative only and are subject to change⁵
 Sanction Hearing (to sanction the Scheme)                                 A date expected to fall during the fourth quarter of 2023 ("T")⁶
 Last day of dealings in, and for the registration of transfers of, and    T + 1 Business Day
 disablement in CREST of, Instem Shares
 Scheme Record Time                                                        6.00 p.m. on T + 1 Business Day
 Suspension of dealings in Instem Shares on AIM                            by 7.30 a.m. on T + 2 Business Days
 Effective Date                                                            T + 2 Business Days⁷
 Cancellation of admission to trading of Instem Shares on AIM              by 7.00 a.m. on T + 3 Business Days
 Latest date for dispatch of cheques, and crediting of CREST accounts and  within 14 days of the Effective Date
 processing electronic transfers due under the Scheme
 Long Stop Date                                                            29 February 2024⁸

Notes

1.     It is requested that BLUE Forms of Proxy for the Court Meeting be
lodged not later than 10.00 a.m. on 17 October 2023 or, if the Court Meeting
is adjourned, 48 hours prior to the time and date set for any adjourned Court
Meeting (excluding any part of such 48-hour period falling on a non-working
day). If the BLUE Form of Proxy for the Court Meeting is not returned by such
time, it may be handed to a representative of Computershare, on behalf of the
Chair of the Court Meeting, or to the Chair of the Court Meeting before the
taking of the poll at the Court Meeting (or any adjournment of it) and it will
be valid.

2.     In order to be valid, the WHITE Forms of Proxy for the General
Meeting must be lodged not later than 10.15 a.m. on 17 October 2023 or, if the
General Meeting is adjourned, 48 hours prior to the time and date set for any
adjourned General Meeting (excluding any part of such 48-hour period falling
on a non-working day).

3.     If either the Court Meeting or the General Meeting is adjourned,
the Voting Record Time for the relevant adjourned Meeting will be 6.00 p.m. on
the date which is two Business Days prior to the date set for such adjourned
Meeting.

4.     General Meeting to commence at 10.15 a.m. or as soon thereafter as
the Court Meeting shall have concluded or adjourned.

5.     These dates are indicative only and will depend, among other
things, on the date upon which: (i) the Conditions are satisfied or (if
capable of waiver) waived; (ii) the Court sanctions the Scheme; and (iii) the
Court Order is delivered to the Registrar of Companies. Instem will give
adequate notice of all of these dates and times, when known, by issuing an
announcement through a Regulatory Information Service, with such announcement
being made available on Instem's website at https://investors.instem.com.
Participants in the Instem Share Plans will be contacted separately regarding
the effect of the Acquisition on their rights under these schemes and provided
with further details concerning the proposals being made to them.

6.     Subject to satisfaction of certain regulatory conditions as set out
in Part 3 (Conditions to and Further Terms of the Scheme and the Acquisition)
of the Scheme Document. In accordance with the terms of the Cooperation
Agreement, the Sanction hearing shall be scheduled to take place on a date
that is not earlier than the date falling twelve Business Days following
satisfaction of the regulatory conditions as set out in Part 3 (Conditions to
and Further Terms of the Scheme and the Acquisition) of the Scheme Document.

7.     Following sanction of the Scheme by the Court, the Scheme will
become Effective in accordance with its terms upon a copy of the Court Order
being delivered to the Registrar of Companies. This is currently expected to
occur within two Business Days after the date of the Sanction Hearing, subject
to satisfaction or (where capable of waiver), waiver of the Conditions, but
could occur on the same day as the Sanction Hearing or the Business Day
following the Sanction Hearing.

8.     This is the latest date by which the Scheme may become Effective.
However, the Long Stop Date may be extended to such later date as Instem,
ARCHIMED and Bidco may agree in writing (with the Panel's consent and as the
Court may approve (should such approval(s) be required)).

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