(Updates)
** Shares of Aerovate AVTE.O sink ~91% to a record low of
$2.25
** Says it will halt enrollment and shut down the late-stage
trial of its lung disease drug after it failed to meet main goal
in mid-stage study
** Drug developer was studying its lead drug, AV-101, a dry
powder inhaled formulation of imatinib, in adults with pulmonary
arterial hypertension (PAH) in a mid-to-late-stage trial
** PAH is characterized by high blood pressure in the
arteries of the lungs
** In the mid-stage study, the drug did not meet its main
goal of improving blood flow from the lung to heart compared to
placebo
** Clearly, this is a worst-case scenario for AVTE shares -
Brokerage Wedbush
** AVTE plans to release full data from the mid-stage trial
at a later date, the timing of which is to be determined
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))