** Shares of Aerovate AVTE.O sink ~91% to $2.26 premarket
** Co says it will halt enrollment and shut down the
late-stage trial of its lung disease drug after it failed to
meet main goal in mid-stage study
** The drug developer was studying AV-101, a dry powder
inhaled formulation of imatinib, in adults with pulmonary
arterial hypertension (PAH) in a mid-to-late-stage trial
** PAH is characterized by high blood pressure in the
arteries of the lungs
** In the mid-stage study, the drug did not meet its main
goal of improving blood flow from the lung to heart compared to
placebo
** Co plans to release full data from the mid-stage trial at
a later date, the timing of which is to be determined
** Up to last close, stock up ~9% YTD
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))