Updates
** Drug developer Jasper Therapeutics' JSPR.O shares fall as much as 66.5% to all-time low of $2.27
** Stock set for its worst day in over 5 months, if losses hold
** Co
halts its asthma trial
for experimental drug briquilimab due to a drug product lot issue that affected potency
** The same manufacturing problem impacted results in an early-stage study treating chronic spontaneous urticaria (CSU), a skin condition that causes red, itchy bumps
** Despite the issues, briquilimab achieved complete response at week 12 in CSU patients who received properly manufactured drug lots
** Jasper is investigating the issue and expects results in the coming weeks
** Despite Jasper's update on manufacturing issues delaying asthma and CSU trials to mid-2026, H.C. Wainwright analyst Emily Bodnar remains "encouraged on efficacy"
** As of last close, stock down 68.33% YTD
(Reporting by Siddhi Mahatole and Kamal Choudhury)
((siddhi.mahatole@thomsonreuters.com))