(Updates)
** Shares of drug developer Kodiak Sciences KOD.O fall
60.2% to $2.9
** Stock top pct loser across U.S. stock exchanges
** KOD says will stop further development of its
experimental eye disease drug, tarcocimab tedromer
** Drug failed to meet main goal in two late-stage studies
testing it as a treatment for diabetes macular edema, a leading
cause of blindness in patients with diabetes
** KOD's drug failed to match Regeneron Pharmaceuticals'
REGN.O Eylea in improving the eye's ability to distinguish
shapes and the details of objects at a given distance
** Co adds an unexpected increase in cataracts was also
observed over time in those receiving KOD's experimental drug
in both late-stage studies
** The drug last year failed to match Eylea in improving the
vision in a mid-to-late-stage trial in patients with a chronic
eye disorder that causes blurred vision or blind spots
** YTD, KOD stock down ~59%
(Reporting by Bhanvi Satija and Pratik Jain in Bengaluru)
((Bhanvi.Satija@thomsonreuters.com; Outside U.S. +91
9873062788;))