** Shares of Krystal Biotech Inc KRYS.O up 16.4% at
$111.82
** Multiple brokerages raise PT on co after U.S. FDA on
Friday approved KRYS's first-of-its kind topical gene therapy
for patients with a genetic skin disorder
** The therapy, Vyjuvek, is expected to be available in the
United States in Q3 of 2023
** Brokerage TD Cowen raises stock PT to $130 from $111
** The $631,000 patient/year WAC (wholesale acquisition
cost) of the therapy and the company's updated estimation of
more than $750 mln in peak sales worldwide, aligns with our
model - TD Cowen
** The company expects to also obtain European approval
around early 2024 and in Japan in 2025
** Brokerage H.C. Wainwright ups PT to $139 from $119, and
Guggenheim raises PT to $130 from $101
** YTD co's stock up 41.2%, including session gains
(Reporting by Pratik Jain in Bengaluru)
((Pratik.Jain@thomsonreuters.com;))