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LENZ — LENZ Therapeutics News Story

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Newly listed Verve Therapeutics, Graphite Bio jump on Intellia breakthrough

** Verve Therapeutics  VERV.O  and Graphite Bio  GRPH.O ,
which both went public this month, jump on Mon in wake of
Intellia Therapeutics'  NTLA.O  breakthrough news
    ** Intellia and partner Regeneron Pharma  REGN.O  over the
weekend posted positive interim data from ongoing early-stage
trial for genome editing candidate, NTLA-2001  urn:newsml:reuters.com:*:nL3N2OA2N8
    ** NTLA-2001 is the first CRISPR/Cas9-based therapy
candidate for precision editing of a gene in a target tissue in
humans
    ** VERV jumps 33.0% to $47.85. Shares of gene editing firm
focused on treating cardiovascular diseases now ~150% above Jun
16 IPO price of $19  urn:newsml:reuters.com:*:nL3N2NZ432
    ** GRPH rises 12.2% to $20.75, after closing up ~9% at
$18.50 in debut on Fri. CRISPR specialist raised $238 mln in IPO
priced at $17, and plans to use proceeds to launch Phase 1/2
clinical trial for its lead drug to treat sickle cell disease
later this year (See filing https://www.sec.gov/Archives/edgar/data/1815776/000119312521200751/d132211d424b4.htm#toc132211_5)

 (Lance Tupper is a Reuters market analyst. The views expressed
are his own)
 ((lance.tupper.tr.com@reuters.net
lance.tupper@tr.com 1-332-219-1430))

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