** Shares of Lexicon Pharmaceuticals LXRX.O rise 3.4% to
$1.81 premarket
** The drugmaker resubmits marketing application for its
experimental diabetes drug, sotagliflozin, to the U.S. Food and
Drug Administration
** Lexicon is seeking approval for sotagliflozin as adjunct
to insulin therapy in patients with type 1 diabetes who have
chronic kidney disease
** The agency in 2019 had declined to approve the drug over
risk of diabetic ketoacidosis (DKA)
** DKA is a life-threatening condition in which acids called
ketones build up when the body starts to use fat instead of
glucose as a source of energy
** LXRX anticipates a six-month review following the
resubmission and potential launch in early 2025
** As of last close, stock is up 14.4% YTD
(Reporting by Pratik Jain in Bengaluru)
((Pratik.Jain@thomsonreuters.com;))