** Shares of United Therapeutics UTHR.O gain 43.88% to $438.50 in premarket trading
** Company says its drug, Tyvaso, met the main goal showing improvement in lung function in a late-stage trial
** The trial studied the use of nebulized Tyvaso inhalation solution for the treatment of idiopathic pulmonary fibrosis - a disease that affects the tissue surrounding the air sacs, or alveoli, in the lungs
** Company intends to use the data from both the trial and another ongoing study to support its application to add IPF to the labeled indications for nebulized Tyvaso
** Shares of MannKind Corp MNKD.O, which collaborates with UTHR for a dry powder version of Tyvaso, rise 35.95% to $6.24 before the bell
** Up to last close, UTHR stock down 13.6% YTD
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))