** Shares of Charles River Laboratories CRL.N down 7.6% at
$252.42 after Jefferies downgrades to "hold" from "buy" on
concerns over biotech funding and slashes PT to Street low of
$280
** CRL among biggest pct losers on S&P 500 index .SPX ,
which is down 1.5%
** Shares of contract research organizations (CROs) have
taken a hit after Medpace Holdings MEDP.O in mid-Feb flagged a
decline in biotech funding, triggering concerns about weakening
client demand for CROs urn:newsml:reuters.com:*:nL4N2V34N4
** CRL, which has forecast 2022 adj EPS of $11.50–$11.75,
said in February it is in a "strong position" for growth even if
the funding environment moderates a bit
** Jefferies says its check-ins with private CROs suggest
demand for CRO services has softened in Q2; also says there is
added risk from increasing restructuring announcements from
biotech firms
** Says CRL's 2022 forecast requires "a very steep ramp" in
the face of likely slowing client demand
** CRL shares down 33% YTD
(Reporting by Amruta Khandekar)
((Amruta.Khandekar@thomsonreuters.com;))