** The Nasdaq biotechnology index .NBI falls 2.8% in
afternoon trade, after having ended 1.4% higher on Monday - on
track to close at its lowest in over a month if losses continue
** Protagonist Therapeutics PTGX.O is biggest pct loser on
index; down about 51% after mixed data from mid-stage study of
ulcerative colitis drug urn:newsml:reuters.com:*:nL3N2WO3K2
** Gossamer Bio GOSS.O also among top pct losers on index
as H.C. Wainwright and Raymond James cut PTs following its bowel
disease drug failure urn:newsml:reuters.com:*:nL3N2WN2B6
** Broader markets also in red as over concerns about
slowing global growth and a more aggressive Federal Reserve,
with quarterly reports from Alphabet and Microsoft due after the
bell urn:newsml:reuters.com:*:nL2N2WO24A
** Biotech stocks have had a few rough months as M&As dry
up and investors prefer private markets over public urn:newsml:reuters.com:*:nL3N2VY329
** iShares Nasdaq Biotechnology ETF IBB.O down 3% while
SPDR S&P Biotech ETF XBI.P slides 5%; both had closed higher
on Monday after two consecutive days of losses
** Up to the last close, XBI and IBB have fallen 27% and
18.6%, respectively, so far this year
(Reporting by Amruta Khandekar)
((Amruta.Khandekar@thomsonreuters.com;))