** U.S.-listed shares of drug developer Mereo BioPharma
Group MREO.O rise 10.5% in extended trade
** Co and partner Ultragenyx Pharmaceutical RARE.O say
their experimental monoclonal antibody drug showed increase in
levels of an indicator of bone formation for treating a type of
genetic disorder in a portion of its trial
** Patients taking the drug, setrusumab, also showed a
"substantial and significant improvement" in bone mineral
density by three months - companies
** Setrusumab is being tested in a mid-to late-stage trial
in pediatric and young adult patients with osteogenesis
imperfecta, a disease in which bones fracture easily
** As of last close, U.S.-listed MREO shares up 40% YTD
(Reporting by Raghav Mahobe)
((Raghav.Mahobe@thomsonreuters.com;))