(Adds Axsome Therapeutics; Updates share movements)
** Biogen BIIB.O shares plunge 28.2 pct to $230.16 as co
and partner Eisai Co Ltd 4523.T say they are ending two
late-stage trials testing Alzheimer's drug aducanumab
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** However, BIIB says it will continue to test other
experimental drugs for the memory-robbing disease
** Share drop translates to over $17.1 bln loss in market
cap for BIIB; up to Wed's close, stock had gained 6.5 pct this
year
** Biggest drop for Biogen since Aug. 1, 2008
** AC Immune ACIU.O shares down 3.4 pct at $4.49; co is
developing Alzheimer's treatments in partnership with Roche AG
ROG.S
** Axsome Therapeutics AXSM.O up 13 pct at $13.59; co has
ongoing late-stage trial for Alzheimer's disease in pipeline
** Neurotrope NTRP.O up ~8 pct at $4.62 after co's
positive comments on its Alzheimer's pipeline in the wake of
Biogen's failure; stock up ~40 pct this year
** Sweden's BioArctic AB BIOAb.ST down 26.3 pct, biggest
one-day drop since a ~30 pct plunge on July 26 last year when
BIIB's data on the Alzheimer's drug failed to enthuse investors
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** vTv Therapeutics Inc VTVT.O , which is also developing a
treatment for Alzheimer's, down 2.2 pct at $1.79
** Voyager Therapeutics VYGR.NB up 3.06 pct at $18.64; co
has very early-stage Alzheimer's treatment in the pipeline
(Reporting by Tamara Mathias and Aakash Jagadeesh Babu in
Bengaluru)
((Tamara.Mathias@thomsonreuters.com; within U.S. +1 646 223
8780, outside U.S. +91 806749 1208; Reuters Messaging:
tamara.mathias.thomsonreuters.com@reuters.net))