** Shares of drug developer Nyrada Inc NYR.AX jump as much
as 8.6% to A$0.315, marking their best day since June 8
** Co announces encouraging efficacy results from a
preclinical study of its oral inhibitor treatment for high
cholesterol, NYX-PCSK9i in a specialised mouse model
urn:newsml:reuters.com:*:nFWN2OA0Y4
** Says results from the preclinical efficacy study showed
NYX-PCSK9i reduced total cholesterol by 46% as a monotherapy,
and 65% when dosed in combination with the statin drug Lipitor
over the study period
** Says no adverse effects were identified and NYX-PCSK9i
was well-tolerated
** Adds that safety pharmacology and toxicology studies of
NYX-PCSK9i will commence in H2 2021 in preparation for a Phase I
first-in-human study, which is set to commence mid-2022
** Stock hits highest since June 16
** Stock up 20.8% so far this year, as of last close
(Reporting by Riya Sharma in Bengaluru)
((Riya.Sharma@thomsonreuters.com;))