RCS - OptiBiotix Health - Consumer study of LPLDL in Cholbiome products

OptiBiotix HealthAnnouncement

01/02/2022 07:00

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RNS Number : 2123A  OptiBiotix Health PLC  01 February 2022

OptiBiotix Health plc

("OptiBiotix" or the "Company")

 

Consumer study of LP(LDL)® in Cholbiome® products

 

OptiBiotix Health plc (AIM:
OPTI), a life sciences business developing compounds to tackle obesity, high
cholesterol, blood pressure, diabetes, announces that its wholly-owned
subsidiary, ProBiotix Health Ltd. ("ProBiotix"), has carried out a consumer
study (n=46) on its CholBiome® products.

 

CholBiome®X3 and CholBiome®BP are ProBiotix's patented and proprietary
formulations developed to reduce cardiovascular disease risk using the
probiotic strain LP(LDL)®, on which a third double-blind, randomised,
placebo-controlled human clinical study was recently published documenting a
statistical significant effect of LP(LDL)® in reducing total cholesterol,
LDL-cholesterol and APO-B : Third human clinical trial LPLDL® in
hypercholesterolemic adults - ScienceDirect
(https://www.sciencedirect.com/science/article/pii/S1756464622000093) .
(RNS: 18 January 2022)

 

Human studies are essential in providing a scientific, clinical, and
statistical evidence base for use of an intervention in a controlled
environment.  However, it's important to check these findings reflect the
real-world use of products which is best assessed by receiving structured
feedback from consumers of a product.

 

The consumer study was carried out by contacting customers who purchased
CholBiome® products from the website https://optibiotix.online
(https://optibiotix.online) .

 

The results of the survey are shown below:-

 

I.     96% of consumers who had taken CholBiome®X3 and who had measured
their total cholesterol levels reported that their levels had reduced.  Of
these:-

a.    17% reported reductions in total cholesterol of >30%

b.    50% reported reductions in total cholesterol of between 16-30%

c.     29% reported reductions in total cholesterol of between 1-15%

II.    88% of consumers stated that their LDL-cholesterol (bad cholesterol)
had been reduced (with 8% not knowing their LDL cholesterol levels).

III.   This level of reduction was sustained with 93% of users who took the
product for more than 1 year reporting reduced levels of total and LDL
cholesterol.

IV.  No consumers taking CholBiome®X3 reported any side effects or tolerance
issues.

 

These results build upon a consumer study carried out in Dec 2019 (n=20) on
CholBiome®X3 in which 95% of users stating that the product was effective,
and 90% reporting they would recommend the product to family and friends.

 

Mikkel Hvid-Hansen, Commercial Director of Probiotics, commented: "The
combination of scientific, clinical, and consumer studies on LP(LDL)®, and
formulations like the CholBiome® product range provide a growing body of
evidence for its safe and effective use in reducing biomarkers of
cardiovascular risk like total cholesterol, LDL cholesterol, and
Apolipoprotein B.  We now have five scientific publications, three human
studies, two consumer studies and numerous positive product reviews which
gives us confidence in the use of LP(LDL)®.  We now feel we have evidence
broadly comparable to Phase I/II pharmaceutical studies which we can use to
open up further partnering or licensing opportunities for use of LP(LDL)® as
an OTC product by itself or in combination with existing treatments (e.g.
statins), or as a drug biotherapeutic in markets outside the USA."

 

For further information, please contact:

 

 OptiBiotix Health plc                                  www.optibiotix.com (http://www.optibiotix.com/)
 Stephen O'Hara, Chief Executive  Contact via Walbrook below

 Cenkos Securities plc (Broker)                         Tel: 020 7397 8900
 Callum Davidson / Neil McDonald
 Michael Johnson / Russell Kerr (Sales)

 Walbrook PR Ltd                                        Mob: 07876 741 001
 Anna Dunphy

 

 

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