** Jefferies raises the Finnish drugmaker Orion ORNBV.HE
to "buy" from "hold" driven by the increased estimates for peak
sales of its prostate cancer drug Nubeqa
** Broker hikes its peak sales estimate for Nubequa, which
was developed jointly by Orion and Bayer BAYGn.DE , to EUR 1.3
billion ($1.46 billion) from EUR 750 million, assuming 27%
royalty rate paid by Bayer on in-market peak sales of over EUR
4.7 billion by 2030
** This follows Bayer's Head of Pharma's comments that
Nubeqa has the potential to be its best-selling product, and
positive doctor feedback, broker says
** Jefferies expects Nubeqa to drive consensus EPS upgrades
and increase headroom for Orion to pay bigger dividends while
lowering the pay-out ratio, with flexibility to materially raise
the dividend from 2026
** The broker adds the phase 3 for another prostate cancer
drug, opevesostat (ODM-208), could potentially replenish Orion's
portfolio post-loss of Nubeqa exclusivity in 2033
** It notes opevesostat could sustain Orion's growth into
the 2030s, with the forecasted EUR 1.1 billion unrisked peak
sales paid by Merck MRK.N
($1 = 0.8933 euros)
(Reporting by Agata Rybska)
((gdansk.newsroom@thomsonreuters.com;))