** Shares in Finnish pharma company Orion ORNBV.HE fall around 10% after it missed Q4 profit estimates
** Jefferies says EBIT missed mainly due to higher‑than‑expected research and development (R&D) costs and a weaker sales mix, especially in branded products
** Orion's Q4 quarterly operating profit is at EUR 328.1 million ($389.78 million), below the Vara Research consensus of EUR 346.7 million
** The stock sits at the bottom of the Helsinki blue chip .OMXH25
($1 = 0.8418 euros)
(Reporting by Elviira Luoma)
((Elviira.luoma@thomsonreuters.com))