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REG-Oxford Instruments: Holding(s) in Company <Origin Href="QuoteRef">OXIG.L</Origin>

TR-1: Notifications of Major Interests in Shares                                                                                                                                                                                                                                     
 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:                                       Oxford Instruments PLC                                                                                                              
 2. Reason for notification (yes/no)                                                                                                                                                                                                                                                  
 An acquisition or disposal of voting rights                                                                                                                                                                        Yes                                                               
 An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached                                                               No                                                                
 An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments                                                                                                         No                                                                
 An event changing the breakdown of voting rights                                                                                                                                                                   No                                                                
 Other (please specify):                                                                                                                                                                                            No                                                                
 3. Full name of person(s) subject to notification obligation:                  Ameriprise Financial, Inc. and its group                                                                                                                                                              
 4. Full name of shareholder(s) (if different from 3):                          HSBC Global Custody Nominee (UK) Limited Nortrust Nominees Limited Securities Services Nominees Limited State Street Bank & Trust Boston State Street Nominees Limited Vidacos Nominees Limited       
 5. Date of transaction and date on which the threshold is crossed or reached:  22 (nd)February 2017                                                                                                                                                                                  
 6. Date on which issuer notified:                                              24 (th)February 2017                                                                                                                                                                                  
 7. Threshold(s) that is/are crossed or reached:                                Above the threshold of 13%                                                                                                                                                                            
                                                                                                                                                                                                                                                                                      

   

 8: Notified Details                                                                                                                                                                 
 A: Voting rights attached to shares                                                                                                                                                 
 Class/type of shares If possible use ISIN code  Situation previous to the triggering transaction      Resulting situation after the triggering transaction                          
                                                 Number of shares           Number of voting rights    Number of shares  Number of voting rights     Percentage of voting rights     
                                                 Direct                                                Direct            Indirect      Direct        Indirect        
 GB0006650450                                    7,001,976                  7,001,976                  37,418            37,418        7,501,993     0.065%          13.091%         

   

 B: Qualifying Financial Instruments                                                                                                                                                           
 Resulting situation after the triggering transaction                                                                                                                                          
 Type of financial instrument  Expiration date  Exercise/ conversion period  No. of voting rights that may be acquired if the instrument is exercised/converted.  Percentage of voting rights  
                                                                                                                                                                                               

   

 C: Financial Instruments with similar economic effect to Qualifying Financial Instruments                                                                               
 Resulting situation after the triggering transaction                                                                                                                    
 Type of financial instrument  Exercise Price  Expiration date  Exercise / conversion period  No. of voting rights instrument refers to  Percentage of voting rights     
                                                                                                                                         Nominal         Delta           
                                                                                                                                                                         

   

 Total (A+B+C)                                         
 Number of voting rights  Percentage of voting rights  
 7,539,411                13.156%                      

   

 9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:                                                                                                                                                                                                                                                                                                                                                                                       
 Threadneedle Asset Management Limited (13.156%)  Threadneedle Asset Management Limited is wholly owned by TC Financing Limited, which is itself wholly owned by Threadneedle Asset Management Holdings Limited, which is itself wholly owned by TAM UK Holdings Limited, which is itself wholly owned by Threadneedle Holdings Limited, which is itself wholly owned by Threadneedle Asset Management Holdings SARL, which is itself wholly owned by Ameriprise International Holdings GmbH, which is itself wholly owned by     
 Ameriprise Financial, Inc.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       

   

 Proxy Voting:                                                          
 10. Name of proxy holder:                                         N/A  
 11. Number of voting rights proxy holder will cease to hold:      N/A  
 12. Date on which proxy holder will cease to hold voting rights:  N/A  

   

 13. Additional information:  The Shares referred to in section 9 of this form are held in portfolios and funds managed on a discretionary basis by the entities set out in section 9. Please note that the Shares are held through certain nominee companies.  
 14 Contact name:             Susan Johnson-Brett, Oxford Instruments plc                                                                                                                                                                                       
 15. Contact telephone name:  01865 393324                                                                                                                                                                                                                      



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