(Updates)
** Shares of drug developer Palisade Bio PALI.O more than
double to four-month high of $1.49
** Co announces positive pre-clinical data for its
experimental therapy, PALI-2108, to treat ulcerative colitis, an
inflammatory bowel disease
** The oral experimental therapy is being developed to
target the phosphodiesterase-4B protein, which plays a role in
inflammation in patients with moderate-to-severely active
ulcerative colitis
** The drug showed significant reductions in symptoms of the
disease and a reduction in weight loss in specific dosage groups
in mice, "showcasing the potential for targeted efficacy" - PALI
** The therapy was safe and well-tolerated in the studies -
PALI
** Co expects to launch an early-stage study testing the
therapy in humans later this year
** Stock fell 76.8% in the last 12 months
(Reporting by Sneha S K)
((Sneha.SK@thomsonreuters.com;))