(Updates)
** Shares of cancer immunotherapy developer PDS
Biotechnology Corp PDSB.O extend premarket gains to rise about
~29% at $8.7
** Stock among top 5 pct. gainers across U.S. stock
exchanges premarket
** Late Thursday, co reported positive interim data from
mid-stage trial testing efficacy of its lead candidate PDS0101
in combination with Merck & Co Inc's MRK.N therapy Keytruda
** Co adds the combination treatment showed an estimated
12-month survival rate of 87% in patients with a type of head
and neck cancer
** Also demonstrated a disease control rate (disease
stabilization or tumor shrinkage) of 70.6% and a
progression-free survival of 10.4 months
** Co, however, adds that the combination treatment has not
yet met median overall survival
** 8% of patients experienced a Grade 3 treatment-related
adverse event without more serious Grade 4 or 5 events - company
** Up to Thursday's close, stock down 49.1% YTD
(Reporting by Pratik Jain in Bengaluru)
((Pratik.Jain@thomsonreuters.com;))