** Shares of PepGen Inc PEPG.O surge ~70% to $8.82 - set
for their best daily pct gain since their May listing
** Co says its experimental therapy, PGN-EDO51, for treating
Duchenne muscular dystrophy (DMD) met the main goal of an
early-stage trial assessing its safety profile urn:newsml:reuters.com:*:nGNX3cgqBS
** Says PGN-EDO51 was generally well tolerated at relevant
doses
** Adds that the drug performed above company's expectations
in the trial, delivering "very high" levels of a molecule,
called oligonucleotide, designed to target the root cause of DMD
** Co plans to initiate a mid-stage study of the drug in H1
2023
** DMD is a rare muscle-wasting disorder that can lead to
progressive weakness and loss of both skeletal and heart muscle
** Including session gains, stock down ~32% since May debut
(Reporting by Raghav Mahobe)
((Raghav.Mahobe@thomsonreuters.com;))