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TR1 - Notification of Major Interest in Shares

For filings with the FSA include the annex

For filings with issuer exclude the annex

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying issuer
of existing shares to which voting rights are                           PHSC Plc
attached:ii

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result
in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to
qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):                             Change of Investment Manager       X

3. Full name of person(s) subject to the                                     Downing LLP
notification obligation:iii

                                                                Downing Income VCT 4 Plc
4. Full name of shareholder(s)
 (if different from 3.):iv                                        Downing Income VCT Plc

5. Date of the transaction and date on
which the threshold is crossed or
reached: v

6. Date on which issuer notified:                                             07/03/2012

7. Threshold(s) that is/are crossed or reached: vi, vii

8. Notified details:

A: Voting rights attached to shares viii, ix

Class/   Situation previous          Resulting situation after the triggering transaction
type of  to the triggering
shares   transaction

if       Number          Number      Number      Number of voting          % of  voting rights
possible of              of          of shares   rights                    x
using    Shares          Voting
the ISIN                 Rights
CODE                                                            Indirect
                                     Direct      Direct xi      xii        Direct  Indirect

         641,499         641,499     641,499     641,499
Ordinary

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of     Expiration     Exercise/              Number of voting             % of voting
financial   date xiii      Conversion Period xiv  rights that may be           rights
instrument                                        acquired if the
                                                  instrument is
                                                  exercised/ converted.

C: Financial Instruments with similar economic effect to Qualifying Financial
Instruments xv, xvi

Resulting situation after the triggering transaction

Type of    Exercise      Expiration Exercise/    Number of voting rights     % of voting rights
financial  price         date xvii  Conversion   instrument refers to        xix, xx
instrument                          period xviii

                                                                             Nominal Delta

Total (A+B+C)

Number of voting rights                     Percentage of voting rights

641,499                                     6.2%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable: xxi

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:                                    Grant Whitehouse, Company Secretary

15. Contact telephone number:                                              0207 416 7780

Note: Annex should only be submitted to the FSA not the issuer

Annex: Notification of major interests in sharesxxii

A: Identity of the persons or legal entity subject to the notification
obligation

Full name

(including legal form of legal entities)

Contact address

(registered office for legal entities)

Phone number & email

Other useful information

(at least legal representative for legal persons)

B: Identity of the notifier, if applicable

Full name

Contact address

Phone number & email

Other useful information

(e.g. functional relationship with the person or legal entity subject to the
notification obligation)

C: Additional information

For notes on how to complete form TR-1 please see the FSA website.

END

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