REG - Polarean Imaging PLC - Order received for upgraded hyperpolariser

Polarean ImagingAnnouncement

03/05/2024 07:00

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RNS Number : 0929N  Polarean Imaging PLC  03 May 2024

Polarean Imaging Plc

("Polarean" or the "Company")

 

Order received for upgraded hyperpolariser

Cincinnati Children's Hospital Medical Center upgrades their existing research
system to provide additional flexibility for research and clinical scanning

 

Polarean Imaging Plc (AIM: POLX), a commercial-stage medical device leader in
advanced Magnetic Resonance Imaging ("MRI") of lung function, announces that
it has received an order for a new polariser to replace the research polariser
at Cincinnati Children's Hospital Medical Center ("Cincinnati Children's").
Cincinnati Children's is ranked as the number one children's hospital for
2023/2024 in the United States by U.S. News & World Report.

 

Cincinnati Children's previously purchased the first clinical polariser and
continues to demonstrate a commitment to the future of Xenon MRI for
challenging lung diseases. Cincinnati Children's performs hospital clinical
imaging on both children and adults (from their neighbouring partner
institution, UC Medical Centre). Led by Dr. Jason Woods, the hospital runs a
robust research programme focused on the Xenon MRI platform technology. The
new polariser will enable Cincinnati Children's to leverage the benefits of
cutting-edge technology and providing flexibility to expand XENOVIEW™
capabilities for their research and clinical patients.

 

Christopher R. von Jako, Ph.D., CEO of Polarean, said: "I commend the ongoing
work of the entire team at Cincinnati Children's, both in research and
clinical care. They consistently recognise the benefits that pulmonary
functional Xenon MRI technology offers to children with chronic lung disease
and have extended access to this technology to the adjacent adult hospital. We
look forward to working closely with their team to ensure a swift
implementation of the new system."

 

Dr. Jason Woods, Director of Research in Pulmonary Medicine at Cincinnati
Children's said: "We are excited to enhance our research capabilities with
Polarean's latest technology. This upgrade will allow us to further explore
the applications of Xenon MRI in paediatric pulmonary care and expand our
current clinical offerings for the benefit of our patients."

 

Enquiries:

 

 Polarean Imaging plc                                        www.polarean.com / www.polarean-ir.com (http://www.polarean-ir.com)
 Christopher von Jako, Ph.D, Chief Executive Officer         Via Walbrook PR
 Charles Osborne, Chief Financial Officer

 Stifel Nicolaus Europe Limited (NOMAD and Sole Corporate Broker)                                  +44 (0)20 7710 7600
 Nicholas Moore / Samira Essebiyea / Kate Hanshaw (Healthcare Investment
 Banking)
 Nick Harland (Corporate Broking)

 Walbrook PR         Tel: +44 (0)20 7933 8780 or polarean@walbrookpr.com
                     (mailto:polarean@walbrookpr.com)
 Anna Dunphy / Phillip Marriage          Mob: +44 (0)7876 741 001 / +44 (0)7867 984 082

 

 

About Polarean

Polarean is a revenue-generating medical imaging technology company
revolutionizing pulmonary medicine through direct visualisation of lung
function by introducing the power and safety of MRI to the respiratory
healthcare community. This community is in desperate need of modern solutions
to accurately assess lung function. The Company strives to optimise lung
health and prevent avoidable loss by illuminating hidden disease, addressing
the global unmet medical needs of more than 500 million patients worldwide
suffering from chronic respiratory disease. Polarean is a leader in the field
of hyperpolarisation science and has successfully developed the first and only
hyperpolarised Xenon MRI inhaled contrast agent, XENOVIEW™, which is now
FDA-approved in the United States. Polarean is dedicated to researching,
developing, and commercialising innovative imaging solutions with its
non-invasive and radiation-free pulmonary functional MRI platform. This
comprehensive drug-device platform encompasses the proprietary Xenon gas
blend, gas hyperpolarisation system, as well as software and accessories,
facilitating fully integrated modern respiratory imaging operations. Founded
in 2012, with offices in Durham, NC, and London, United Kingdom, Polarean is
committed to increasing global awareness of and broad access to its XENOVIEW
MRI technology platform. For the latest news and information about Polarean,
please visit www.polarean.com (http://www.polarean.com/) .

XENOVIEW IMPORTANT SAFETY INFORMATION

 

Indication

XENOVIEW™, prepared from the Xenon Xe 129 Gas Blend, is a hyperpolarized
contrast agent indicated for use with magnetic resonance imaging (MRI) for
evaluation of lung ventilation in adults and pediatric patients aged 12 years
and older.

 

Limitations of Use

XENOVIEW has not been evaluated for use with lung perfusion imaging.

 

CONTRAINDICATIONS

None.

 

Warnings and Precautions

Risk of Decreased Image Quality from Supplemental Oxygen: Supplemental oxygen
administered simultaneously with XENOVIEW inhalation can cause degradation of
image quality. For patients on supplemental oxygen, withhold oxygen inhalation
for two breaths prior to XENOVIEW inhalation, and resume oxygen inhalation
immediately following the imaging breath hold.

 

Risk of Transient Hypoxia: Inhalation of an anoxic gas such as XENOVIEW may
cause transient hypoxemia in susceptible patients. Monitor all patients for
oxygen desaturation and symptoms of hypoxemia and treat as clinically
indicated.

 

Adverse Reactions

Adverse Reactions in Adult Patients: The adverse reactions (> one patient)
in efficacy trials were oropharyngeal pain, headache, and dizziness.  Adverse
Reactions in Pediatric and Adolescent Patients: In published literature in
pediatric patients aged 6 to 18, transient adverse reactions were reported:
blood oxygen desaturation, heart rate elevation, numbness, tingling,
dizziness, and euphoria. In at least one published study of pediatric patients
aged 6 to 18 years, transient decrease in SpO2% and transient increase in
heart rate was reported following hyperpolarized xenon Xe 129 administration.
XENOVIEW is not approved for use in pediatric patients less than 12 years of
age.

 

Please see full prescribing information at www.XENOVIEW.net

 

PLC-RNS-2331

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