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RNS Number : 2434I Poolbeg Pharma PLC 20 November 2025
Poolbeg Pharma plc
POLB 001 European Patent granted
Further strengthens Poolbeg's global intellectual property portfolio
20 November 2025 - Poolbeg Pharma (https://www.poolbegpharma.com/) (AIM:
POLB, 'Poolbeg' or the 'Company'), a clinical-stage biopharmaceutical company
with a core focus on transforming the cancer immunotherapy field, announces
that the European Patent Office has granted Poolbeg's European Immunomodulator
II patent application covering POLB 001 for the treatment of severe influenza.
POLB 001 is a potent and selective p38 MAP kinase inhibitor with strong
potential across multiple disease areas, including the prevention and
treatment of cancer immunotherapy-induced Cytokine Release Syndrome ("CRS"), a
potential market opportunity of over US$10 billion, and the treatment of
severe influenza. POLB 001 holds the potential to address significant unmet
needs affecting patients and healthcare systems globally.
Poolbeg is actively building a comprehensive, worldwide IP portfolio, with
patents covering use of p38 MAPK inhibitors in patients with severe influenza
and for the prevention and treatment of cancer immunotherapy-induced CRS. This
patent grant further strengthens the Company's robust intellectual property
portfolio, enhancing POLB 001's value and appeal to potential partners.
Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma, said:
"This patent grant from the European Patent Office highlights the strong
progress we continue to make in developing and strengthening our IP portfolio
for POLB 001 across multiple disease indications. This further enhances the
value and attractiveness of POLB 001 for potential partners."
Enquiries
Poolbeg Pharma Plc +44 (0) 207 183 1499
Jeremy Skillington, CEO ir@poolbegpharma.com (mailto:ir@poolbegpharma.com)
Ian O'Connell, CFO
Cavendish Capital Markets Ltd (NOMAD & Joint Broker) +44 (0) 207 220 0500
Geoff Nash, Trisyia Jamaludin (Corporate Finance)
Nigel Birks (Life Science Specialist Sales)
Harriet Ward (ECM)
Shore Capital Stockbrokers Ltd (Joint Broker) +44 (0) 207 408 4090
David Coaten, Harry Davies-Ball (Corporate Advisory)
Malachy McEntyre (Corporate Broking)
J&E Davy (Joint Broker) +353 (0) 1 679 6363
Anthony Farrell, Niall Gilchrist
Optimum Strategic Communications +44 (0) 208 078 4357
Nick Bastin, Vici Rabbetts, Elena Bates poolbeg@optimumcomms.com (mailto:poolbeg@optimumcomms.com)
About Poolbeg Pharma plc
Poolbeg Pharma plc (AIM: POLB) is a clinical-stage
biopharmaceutical company with a core focus on transforming the cancer
immunotherapy field. The Company's lead asset, POLB 001, has the potential to
expand administration of cancer immunotherapies from centralised specialist
cancer centres into community hospitals by making the treatments safer through
the prevention of the life-threatening side effect, Cytokine Release Syndrome
(CRS). As such, POLB 001 could increase the number of patients that can
receive these life-saving treatments, thereby increasing the market
opportunity. Poolbeg is also advancing the development of a patient-friendly
therapy for obesity with an oral encapsulated GLP-1, offering a differentiated
approach within one of the world's largest markets. With multiple near-term
clinical value inflection points, and an experienced team with a proven track
record, Poolbeg is focussed on partnering its high value programmes that are
targeting large markets and addressing critical unmet medical needs.
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Forward-Looking Statements
This announcement may contain forward-looking statements and the words
"expect", "anticipate", "intends", "plan", "estimate", "aim", "forecast",
"project" and similar expressions (or their negative) identify certain of
these forward-looking statements. The forward-looking statements in this
announcement are based on numerous assumptions and Poolbeg's present and
future business strategies and the environment in which Poolbeg expects to
operate in the future. Forward-looking statements involve inherent known and
unknown risks, uncertainties and contingencies because they relate to events
and depend on circumstances that may or may not occur in the future and may
cause the actual results, performance or achievements to be materially
different from those expressed or implied by such forward-looking statements.
These statements are not guarantees of future performance or the ability to
identify and consummate investments. Many of these risks and uncertainties
relate to factors that are beyond Poolbeg's ability to control or estimate
precisely, such as future market conditions, currency fluctuations, the
behaviour of other market participants, the outcome of clinical trials, the
actions of regulators and other factors such as Poolbeg's ability to obtain
financing, changes in the political, social and regulatory framework in which
Poolbeg operates or in economic, technological or consumer trends or
conditions. Past performance should not be taken as an indication or guarantee
of future results, and no representation or warranty, express or implied, is
made regarding future performance. No person is under any obligation to update
or keep current the information contained in this announcement or to provide
the recipient of it with access to any additional relevant information.
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