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REG - Proteome Sciences - Interim Results

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RNS Number : 8551U  Proteome Sciences PLC  04 August 2022

 

 

 

Prior to publication, the information contained within this announcement was
deemed by the Company to constitute inside information as stipulated under the
UK Market Abuse Regulation. With the publication of this announcement, this
information is now considered to be in the public domain

                                                                                                                                                                                    4 August 2022

 

Proteome Sciences plc

("Proteome Sciences" or the "Company")

 

Interim results for the six months ended 30 June 2022

 

Proteome Sciences announces its unaudited interim results for the six months
ended 30 June 2022.

 

Financial highlights:

·    Proteomics services revenues £0.85m (H1 2021: £0.68m)

·    TMT(®) reagent sales and royalties £2.39m (H1 2021: £1.29m)

·    Total revenues £3.24m (H1 2021: £1.97m)

·    Gross profit £1.80m (H1 2021: £1.16m)

·    Costs £2.98m (H1 2021: £2.23m)

·    Profit before tax £0.07m (H1 2021: loss before tax of £0.41m)

·    Adjusted EBITDA** £0.64m (H1 2021: loss of £0.11m)

 

Commenting on these results, Dr. Mariola Soehngen, Chief Executive Officer of
Proteome Sciences, said:

 

"We have seen further positive momentum in sales of our services and TMT(®)
reagents during the first half of 2022 as we continue to implement our
strategy of organic growth.

 

TMT(®) sales were £1.45m in H1 2022 vs £0.67m in H1 2021, an increase of
116%. Royalties increased from £0.61m to £0.94m (54%).

 

Our revenues from TMT(®) and TMTpro™ reagents remain the most significant
source of income and are close to double the same period last year as the
research world globally starts to re-engage fully after the COVID pandemic.
Whilst we expect the rate of growth to slow marginally in the second half, we
expect a substantial improvement for the full year.

 

The market response to TMTpro™ 18plex reagents has been very positive as new
automation platforms enabling higher throughput labelling have been introduced
to the market. We still see challenges from label-free methods and continue to
look to further extend the value of TMT™ reagents across newly emerging
sectors such as single cell and low content proteomics, as well as leveraging
our chemical expertise in the tagging space to other opportunities.

 

Our service business started 2022 with a strong order book and large bank of
samples, allowing us to be at near full capacity since the start of the year.
We report another strong first half with revenues up 25% over the same period
in 2021, building on the growth posted in previous years. Revenue from key
longer term projects begun in H1 will be recognised in the second half of the
year. We have seen a continued high volume of client orders through this
period and remain confident that full year service revenue will show continued
growth over 2021.

 

During this period we have also been working on the introduction of Single
Cell Proteomics (SCP) as a new service, which will be known as SysQuant® SCP,
and evaluating new classes of reagents for mass spectrometry.  To this end we
have added the cellenONE platform in July 2022 which enables us to scale up
the SysQuant® SCP service as we grow the market. Our demonstrated expertise
in TMT(®) reagents and services clearly differentiates us from other players
in the delivery of this complex SysQuant® SCP service.  Further investments
in our resources i.e. staff and instruments have been necessary to maintain
the high level of operational and scientific support our customers receive.

 

Conferences and trade shows have restarted in a new combination of both
physical and virtual attendance.   We have an intensive programme of
customer engagement largely centred around these events.  In early Q2 we
launched a new corporate image largely based on our new web site appearance."

 

**Adjusted EBITDA (a non-GAAP company specific measure which is considered to
be a key performance indicator of the Group's financial performance).

 

 

 

 

For further information:

 Proteome Sciences plc
 Dr Mariola Soehngen, Chief Executive Officer         Tel: +44 (0)20 7043 2116
 Dr Ian Pike, Chief Scientific Officer
 Richard Dennis, Chief Commercial Officer
 Allenby Capital Limited (AIM Nominated Adviser & Broker)
 John Depasquale / Jeremy Porter (Corporate Finance)  Tel: +44 (0) 20 3328 5656

 Tony Quirke (Sales)

 

 

 

About Proteome Sciences plc. (www.proteomics.com (http://www.proteomics.com/)
)

Proteome Sciences plc is a specialist provider of contract proteomics services
to enable drug discovery, development and biomarker identification, and
employs proprietary workflows for the optimum analysis of tissues, cells and
body fluids.  SysQuant(®) and TMT(®)MS2 are unbiased methods for
identifying and contextualising new targets and defining mechanisms of
biological activity, while analysis using Super-Depletion and TMTcalibrator™
provides access to over 8,500 circulating plasma proteins for the discovery of
disease-related biomarkers. Targeted assay development using mass spectrometry
delivers high sensitivity, interference-free biomarker analyses in situations
where standard ELISA assays are not available.

 

The Company has its headquarters in Cobham, UK, with laboratory facilities in
Frankfurt, Germany.

 

 

 

 

 

 

 

 

 

 

 

Chief Executive Officer's Report

Services

Recognised revenues from the proteomics services business increased 25% in the
first half to £0.85m (2021: £0.68m) reflecting the strong order book and
banked samples we carried forward from 2021.  We invoiced our first project
that involved data generated from the Meso Scale Discovery platform that we
acquired last year.

 

In H1 2022, we booked new orders worth over £1.21m, representing a 14%
increase over H1 2021 (£1.06m) with a split between US (64%) and European
(36%) customers.  We also maintained a strong level of repeat orders from
existing customers, which accounted for 45% of the total by value, as we
become established as preferred suppliers.

 

Revenue prospects for H2 look strong as we continue to have a healthy order
book and pipeline of projects to deliver by the year end.

 

As we moved into 2022 global travel has resumed, making it possible again to
have face to face meetings with our clients and prospects. We continue to use
a mixture of videoconferencing and presentations and attend (both in person
and virtually) trade shows to broaden further our outreach and customer
base.  We use these outreach opportunities to maintain contact with our
current customers, establish new accounts and look for new business
opportunities in markets that we plan to enter in the coming months, for
example single cell proteomics.

 

TMT(®)

Revenues from sales of TMT(®) and TMTpro™ reagents and royalties were
£2.39m (2021: £1.29m) driven by significant increases in global research and
development activities as we begin to live with COVID. The launch of TMTpro™
18plex reagents and new formulations through our Licensee Thermo Scientific
have been very well received in the market and we expect strong sales to
continue through the rest of the year, although growth rates are expected to
slow in the fourth quarter. We have ample stocks of all reagents to meet
demand over the next 18 - 24 months and will be making a new batch of
TMTpro™ during the second half of this year, ensuring supplies beyond 36
months.

 

Historically, many groups have held back from using isobaric tagging due to
perceived challenges of sample preparation. Whilst these concerns are not well
founded, the recent introduction of automated sample preparation systems from
Preomics, Thermo Scientific and Cellenion are supporting greater uptake of
TMT(®) and particularly TMTpro™. We expect this trend will continue as
users start to see the benefits of high precision in biomarker discovery
experiments, compared with label free methods.

 

The strong response to 18plex TMTpro™ has been accompanied with market
demand for even higher plexing rates and we have initiated research into new
tag designs that will potentially address this demand, in the longer term. Our
TMTpro™ reagents are covered by patents in Europe, the USA and other major
territories until the mid-2030's and we remain active alongside our licensee
Thermo Scientific in protecting our markets as we also look to generate new
intellectual property.

 

Outlook

Revenue for the H2 looks strong as we continue to have a healthy order book
for our services backed up by a pipeline of projects for delivery in the next
period together with the introduction of a new SysQuant® SCP service. We
expect strong sales of TMTpro™ 18plex reagents in the coming months fuelled
by the introduction of various automation systems with perhaps a reduction in
the rate of growth in Q4 2022 as we continue to develop new reagents for
multiplexed mass spectrometry.

 

We remain confident that full year revenues from our services and TMT(® )
will continue to show good growth over 2021.

 

Dr. Mariola Soehngen

Chief Executive Officer

4 August 2022

Finance Director's Report

Revenues in the first half of 2022 were 64% higher at £3.24m compared to the equivalent period in 2021 (£1.97m), TMT(®) and TMTpro™ sales increased to £1.45m (30 June 2021: £0.67m). Proteomics service sales increased to £0.85m (30 June 2021: £0.68m).  We expect high demand for the service business extending into the H2 half of 2022.

 

Costs of sales and administrative expenses increased by 33% to £2.98m (30
June 2021: £2.23m). This was as a result of investment in instruments and
increased orders resulting in additional personnel and material costs. So far
very prominent cost drivers like electricity costs remained largely stable but
we expect price increases in the upcoming 6 months in line with almost all our
material costs. Financing costs for the first half increased to £0.19m in
comparison with £0.14m in the previous period due to increases of interest
rates by the Bank of England.

( )

The profit before taxation amounted to £0.07m (30 June 2021: a loss of
£0.41m), which represents a significant positive increase by almost £0.50m.
Similarly EBITDA increased to £0.53m (2021: loss £0.18m) and adjusted
EBITDA** increased to £0.64m (2021: loss £0.11m). This is primarily
attributable to increased sales and royalties of TMT(®) and TMTpro™
reagents, which we anticipate remaining at a high level for the rest of the
year.   As at 30 June 2022 the Group had cash resources of £3.20m (30 June
2021: £2.14m).

 

 

 

          Six months    Six months

          ended         ended

          30 June       30 June

          2022          2021

          (unaudited)   (unaudited)

          £'000         £'000

 

 Continuing operations
 Revenue                                      3,243        1,969
 Gross Profit                                 1,802        1,158

 Administrative Expenses *                    (1,535)      (1,422)
 Operating Profit                             267          (264)
 Depreciation                                 259          78
 EBITDA                                       526          (186)

 Non-cash item: share based payment expenses  118          75
 Adjusted EBITDA **                           644          (111)

 

* Administrative expenses include depreciation

**Adjusted EBITDA (a non-GAAP company specific measure which is considered to
be a key performance indicator of the Group's financial performance).

 

 

 
Stefan Fuhrmann
Finance Director

4 August 2022

 
Consolidated income statement
For the six months ended 30 June 2022

 

 

 

                                                                                                                          Six months    Six months

                                                                                                                          ended         ended

                                                                                                                          30 June       30 June

                                                                                                                          2022          2021

                                                                                                                          (unaudited)   (unaudited)

                                                                                                 Note                     £'000         £'000

 

 Continuing operations
 Revenue
 Licences, sales & services            3,243        1,969

 Cost of sales                         (1,441)      (811)

 Gross profit                          1,802        1,158

 Administrative expenses               (1,535)      (1,422)

 Operating profit / loss               267          (264)

 Finance costs                         (192)        (144)

 Profit / loss before taxation         75           (408)
 Tax                                   (12)         (17)

 Profit / loss for the period          63           (425)

 Profit / loss per share               2
 Basic                                 0.02p        (0.14p)

 Diluted                               0.02p        (0,14p)

 

 
Consolidated statement of comprehensive income
For the six months ended 30 June 2022

 

 

         Six months    Six months

         ended         ended

         30 June       30 June

         2022          2021

         (unaudited)   (unaudited)

         £'000         £'000

 

  Profit/(loss) for the period                               63       (425)

 Other comprehensive income for the period

 Exchange differences on translation of foreign operations   50       15

                                                             113      (410)

 Total comprehensive Income/(expense) for the period

 

 

Consolidated balance sheet

As at 30 June 2022

                                                30 June                     31 December

                                                2022                        2021

                                                (unaudited)                 (audited)

                                                £'000                       £'000
     Non-current assets
     Goodwill                                               4,218           4,218
     Property, plant and equipment                          261             219
     Right-of-use asset                                     834             1,050
                                                            5,313           5,487
     Current assets
     Inventories                                            1,038           1,088
     Trade and other receivables                            864             604
     Contract assets                                        552             479
     Cash and cash equivalents                              3,199           2,387
                                                            5,653           4,558

     Total assets                                           10,966          10,045

     Current liabilities
     Trade and other payables                               (626)           (599)
     Contract liabilities                                   (676)           (35)
     Borrowings                                             (10,997)        (10,825)
     Lease Liabilities                                      (206)           (260)
                                                            (12,505)        (11,719)

     Net current liabilities                                (6,852)         (7,161)

     Non-current liabilities
     Lease liabilities                                      (479)           (602)
     Pension Provisions                                     (526)           (499)
     Total non-current liabilities                          (1,005)         (1,101)
     Total liabilities                                      (13,510)        (12,820)
     Net liabilities                                        (2,544)         (2,775)
     Equity
     Share capital                                          2,952           2,952
     Share premium account                                  51,466          51,466
     Share-based payment reserve                            4,311           4,193
     Merger reserve                                         10,755          10,755
     Translation and others reserve                         (78)            (128)
     Retained loss                                          (71,950)        (72,013)

     Total shareholders deficit                             (2,544)         (2,775)

Consolidated cash flow statement

 For the six months to 30 June 2022

 

                                                                                                                                                           Six months    Six months

                                                                                                                                                           ended         ended

                                                                                                                                                           30 June       30 June

                                                                                                                                                           2022          2021

                                                                                                                                                           (unaudited)   (unaudited)

                                                                                                                                                           £'000         £'000

 

 Profit after tax                                                       63      (425)
 Adjustments for:
 Net finance costs                                                      192     144
 Depreciation of property, plant and equipment and right of use assets  259     78

 Tax charge /(credit)

                                                                        12      17
 Share-based payment expense                                            118     75

 Operating cash outflows before movements in working capital            644     (111)
 Decrease/(increase) in inventories                                     50      (31)
 (Increase)/decrease in receivables                                     (333)   266
 Increase/(decrease in payables                                         668     (120)
 (Decrease)/increase in provisions                                      27      (5)

 Cash generated from / (used in) operations                             1,056   (1)

 Tax paid                                                               (12)    (17)
 Net cash Inflow/(outflow from operating activities                     1,044   (18)
 Cash flows from investing activities
 Purchases of property, plant and equipment                             (84)    (8)

 Net cash outflow from investing activities                             (84)    (8)

 Financing activities

 Lease payments                                                         (198)   (83)
 Net cash outflow from financing activities                             (198)   (83)

 Net Increase/(decrease) in cash and cash equivalents                   762     (109)
 Cash and cash equivalents at beginning of period                       2,387   2,210
 Effect of foreign exchange rate changes                                50      43

 Cash and cash equivalents at end of period                             3,199   2,144

 

Notes

 

For the six months to 30 June 2022

 

1        Basis of preparation and accounting policies

          These interim consolidated financial statements have been
prepared using accounting policies based on UK adopted International
Accounting Standards and Interpretations in conformity with the requirements
of the Companies Act 2006. They do not include all disclosures that would
otherwise be required in a complete set of financial statements and should be
read in conjunction with the 31 December 2021 Annual Report. The financial
information for the half years ended 30 June 2022 and 30 June 2021 does not
constitute statutory accounts within the meaning of Section 434 (3) of the
Companies Act 2006 and both periods are unaudited.

 

          The annual financial statements of Proteome Sciences plc
('the Group') are prepared in accordance with UK adopted International
Accounting Standards and Interpretations in conformity with the requirements
of the Companies Act 2006. The comparative financial information included
within this report does not constitute the full statutory Annual Report for
that period. The statutory Annual Report and Financial Statements for 2021
have been filed with the Registrar of Companies. The Independent Auditors'
Report on the Annual Report and Financial Statements for the year ended 31
December 2021 was unqualified.

 

The directors have concluded that the Group has adequate resources to continue
operational existence for the foreseeable future.  Accordingly, they continue
to adopt the going concern basis in preparing the half-yearly consolidated
financial statements.

 

          Proteome Sciences plc has applied the same accounting
policies and methods of computation in its interim consolidated financial
statements as in its 2021 annual financial statements.

 

There have been no new standards adopted since the presentation of the
financial statements for 2021.

 

The Board of Directors approved this interim report on 4 August 2022.

 

2.       Profit/(loss) per share from continuing operations

 

                                                                         Six months                                    Six months

                                                                         ended                                         ended

                                                                         30 June                                       30 June

                                                                         2022                                          2021

                                                                         (unaudited)                                   (unaudited)

     Profit/(loss) per share
                       Profit/loss for the purpose of basic profit/loss per share being net
                       profit/loss attributable to equity holders of the parent (£'000)

                                                                                                  63                                           (425)

  Number of shares
 Weighted average number of ordinary shares for the purpose of basic loss per                     295,182,056
 share

                                                                                                                                 295,182,056

 Weighted average number of ordinary shares for the purpose of diluted loss per                   306,020,097
 share

                                                                                                                                 295,182,056

 

 

 

 

3.         Cautionary statement

 

          This document contains certain forward-looking statements
relating to Proteome Sciences plc ('the Group'). The Group considers any
statements that are not historical facts as "forward-looking statements". They
relate to events and trends that are subject to risk and uncertainty that may
cause actual results and the financial performance of the Group to differ
materially from those contained in any forward-looking statement. These
statements are made by the directors in good faith based on information
available to them and such statements should be treated with caution due to
the inherent uncertainties, including both economic and business risk factors,
underlying any such forward-looking information.

 

 

 

 

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