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RNS Number : 2669O Proteome Sciences PLC 02 October 2023
2 October 2023
Proteome Sciences plc
("Proteome Sciences" or the "Company")
Launch of Commercial Single Cell Proteomics Services
Proteome Sciences plc is pleased to announce the launch of SysQuant® SCP, the
commercial service for single cell proteomics using the power of its TMTpro™
isobaric labelling reagents. Where more traditional approaches can measure a
few 10s of proteins on each cell using antibody labelling, SysQuant® SCP can
identify more than 1,000 proteins in each study of 576 single cells and
provides novel insights into individual cell biology and heterogeneity.
Proteome Sciences is one of the first commercial providers of such studies
which are expected to significantly improve the performance of drug
development across multiple diseases including cancer, neurodegeneration,
respiratory and cardiac health, and metabolic disorders. Whilst in its
infancy, the field of single cell proteomics is expected to grow rapidly as
drug developers look to integrate single cell genomic data with knowledge of
protein changes. At the same time, the complexity of the process along with
the need to purchase and maintain costly equipment represents a significant
barrier to entry.
The SysQuant® SCP pipeline generates and analyses quantitative mass
spectrometry data to reveal subtle changes not only in individual cells but
also within sub-populations of that same main cell type. This data will
greatly improve understanding of the biological drivers of heterogeneity and
evolution in the contexts of disease and response to therapy, which will offer
new therapeutic and diagnostic targets for personalized medicine.
Commenting on the launch of SysQuant® SCP, Dr. Ian Pike Chief Scientific
Officer stated:
"This is an important step for Proteome Sciences as we have adapted
cutting-edge techniques developed in academia to make them available to the
pharmaceutical and biotechnology industries through SysQuant® SCP. We have
built a robust platform that will provide customers with transformational data
enabling a deeper understanding of disease biology and how drugs are
interacting with their targets. SysQuant® SCP studies are highly
complementary to our established workflows performed on larger samples and
open up a new customer base needing access to this valuable novel single
cell information."
Dr. Mariola Soehngen, Chief Executive Officer commented:
"We are pleased to be one of the first CROs providing single cell proteomics
to our customers. The launch of SysQuant® SCP is part of our growth strategy
along with the opening of a US facility in San Diego. We believe that
broadening our range of services and increasing capacity are essential as the
wider pharmaceutical industry increasingly recognises the need to study
changes in protein expression and function to further advance and accelerate
the drug development process."
Proteome Sciences plc
Dr. Mariola Soehngen, Chief Executive Officer Tel: +44 (0)20 7043 2116
Dr. Ian Pike, Chief Scientific Officer
Richard Dennis, Chief Commercial Officer
Abdelghani Omari, Chief Financial Officer
Allenby Capital Limited (Nominated Adviser & Broker)
John Depasquale / Jeremy Porter (Corporate Finance) Tel: +44 (0) 20 3328 5656
Stefano Aquilino / Tony Quirke (Equity Sales & Corporate Broking)
About Proteome Sciences plc. (www.proteomics.com (http://www.proteomics.com/)
)
Proteome Sciences plc is a specialist provider of contract proteomics services
to enable drug discovery, development and biomarker identification, and
employs proprietary workflows for the optimum analysis of tissues, cells and
body fluids. SysQuant® and TMT®MS2 are unbiased methods for identifying and
contextualising new targets and defining mechanisms of biological activity,
while analysis using Super-Depletion and TMTcalibrator™ provides access to
over 8,500 circulating plasma proteins for the discovery of disease-related
biomarkers. Targeted assay development using mass spectrometry delivers high
sensitivity, interference-free biomarker analyses in situations where standard
ELISA assays are not available.
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