REG - Provexis PLC - Exercise of Options and Total Voting Rights

ProvexisAnnouncement

17/05/2022 12:45

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RNS Number : 8101L  Provexis PLC  17 May 2022

17 May 2022

 

Provexis plc

 

("Provexis" or the "Company")

 

Exercise of Options and Total Voting Rights

 

Provexis, the business that develops, licenses and sells the proprietary,
scientifically-proven Fruitflow® heart-health functional food ingredient,
announces that application has been made for the admission to AIM of 7,000,000
ordinary shares of 0.1p each in the Company ('New Provexis Shares'), pursuant
to the exercise of options by a consultant to the Company.

 

The New Provexis Shares will when issued rank pari passu in all respects with
the existing ordinary shares of 0.1p each in Provexis. Application has been
made to the London Stock Exchange for the 7,000,000 New Provexis Shares to be
admitted to trading on AIM. It is expected that admission will become
effective and that trading in the New Provexis Shares will commence on or
around 23 May 2022 ('Admission').

 

Following Admission, the Company's enlarged issued share capital will comprise
2,217,821,523 ordinary shares with voting rights. The Company does not hold
any shares in treasury. This figure of 2,217,821,523 ordinary shares may be
used by shareholders in the Company as the denominator for the calculations by
which they will determine if they are required to notify their interest in, or
a change in their interest in, the share capital of the Company under the
FCA's Disclosure Guidance and Transparency Rules.

 

 

For further information please contact:

 

 Provexis plc                 Tel:         07490 391888

 Dawson Buck, Chairman                        enquiries@provexis.com

 Ian Ford, CEO

 Allenby Capital Limited      Tel:         020 3328 5656

 Nick Naylor / Liz Kirchner

 

 

Notes for editors

 

About Provexis plc

AIM-listed Provexis is focused on the development, licensing and sales of its
proprietary, scientifically-proven Fruitflow® heart-health functional food
ingredient.

 

Fruitflow is a natural, breakthrough ingredient that helps with platelet
aggregation. This helps promote normal blood flow and circulation, which in
turn benefits cardiovascular health. Fruitflow helps the platelets to
circulate freely and smoothly throughout your blood, without sticking to one
another or to the blood vessels themselves. Freely flowing blood helps reduce
stress on your cardiovascular system.

 

Fruitflow is a highly concentrated form of bioactives which is lycopene-free
and contains over 30 known anti-platelet compounds. Published clinical studies
have shown that Fruitflow works to maintain healthy blood flow in a similar
way to 75mg aspirin but with a milder and reversible action; Fruitflow has a
similar antiplatelet effect to a single dose of aspirin - but when taken
daily, it has none of aspirin's side effects.

 

The science behind Fruitflow has been validated by leading peer review
publications and regulatory authorities. Fruitflow is the only natural
antiplatelet to have a health claim approved by the European Food Safety
Authority, stating that 150mg of Fruitflow 'helps maintain normal platelet
aggregation, which contributes to healthy blood flow'.

 

Provexis entered into a long-term Alliance Agreement with DSM Nutritional
Products in 2010 to commercialise Fruitflow through sales as an ingredient to
brand owners in the food, beverage and dietary supplement categories. More
than 100 regional consumer healthcare brands have now been launched by direct
customers of DSM, and a number of further regional brands have been launched
through DSM's distributor channels.

 

Fruitflow has a number of specific health benefits which have been reflected
in separate patent filings for the use of Fruitflow in:

 

·    mitigating exercise-induced inflammation;

·    managing blood pressure; and

·    protecting against the adverse effects of air pollution on the body's
cardiovascular system. Laboratory work has shown that Fruitflow can reduce the
platelet activation caused by airborne particulate matter, such as that from
diesel emissions, by approximately one third.

 

Provexis sells a high quality dietary supplement product containing Fruitflow
and Omega-3 from its website www.fruitflowplus.com
(http://www.fruitflowplus.com) on a mail order basis. The product is also
available to purchase from Amazon.co.uk and from Holland & Barrett.

 

In November 2021 Provexis entered into a long term supply and distribution
agreement for Fruitflow with By-Health Co., Ltd. ('By-Health'), a £4bn listed
Chinese dietary supplement business, to support the planned launch of some
Fruitflow based products in the Chinese market.

 

The planned launch is progressing well with potential sales volumes remaining
at a significant multiple of existing Fruitflow sales.

 

By-Health has made a significant investment in eight separate studies in
China, at its sole expense, in support of the Fruitflow based products which
it plans to launch in China.

 

The five completed studies showed excellent results in use for Fruitflow, and
they provide strong evidence for its efficacy on platelet functions. The
Chinese regulatory system for functional health food ingredients such as
Fruitflow is governed by the State Administration for Market Regulation
(SAMR), China's top market regulator, and it is based on a defined list of 27
permitted health function claims which brand owners are permitted to use on
product labels.

 

By-Health is working on an extensive regulatory submission to the SAMR for
Fruitflow, seeking to establish a new permitted health function claim for food
ingredients such as Fruitflow that can demonstrate an anti-platelet effect,
addressing the aberrant blood clots which can lead to heart attacks and
strokes.

 

If By-Health is successful in obtaining a new permitted health function claim
it is currently expected that this would result in some significant orders for
Fruitflow, potentially at a multiple of current total sales values.

 

COVID-19

In September 2020 Fruitflow was recognised in a review article by the
Frontiers in Nutrition journal
www.frontiersin.org/articles/10.3389/fnut.2020.583080/full
(http://www.frontiersin.org/articles/10.3389/fnut.2020.583080/full) which
stated that nutraceuticals such as Fruitflow may serve as:

 

'A safe antiplatelet prophylactic treatment for those at high risk of COVID-19
who may also be at increased risk of thrombotic complications and an
alternative to pharmacological compounds that may cause greater risk of
bleeding.'

 

Provexis was founded in 1999 and is headquartered in Reading, Berkshire.

 

Provexis shares are traded on the AIM market of the London Stock Exchange
under the ticker symbol PXS.

 

For further information, please visit www.provexis.com
(http://www.provexis.com) and www.fruitflowplus.com
(http://www.fruitflowplus.com) .

 

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