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RNS Number : 0761T Redx Pharma plc 15 March 2023
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INDIRECTLY, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD
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REDX PHARMA PLC
("Redx" or "the Company")
Statement re: Jounce Therapeutics Press Release
Alderley Park, UK 15 March 2023 Redx Pharma ("Redx", AIM: REDX), the
clinical-stage biotechnology company focused on discovering and developing
novel, small molecule, highly targeted therapeutics for the treatment of
cancer and fibrotic disease, notes the announcement from Jounce Therapeutics
(NASDAQ: JNCE) ("Jounce"), issued last night, regarding the receipt of an
unsolicited and non-binding proposal to acquire 100% of the equity of Jounce
from Concentra Biosciences, LLC.
On 23 February 2023, the boards of Redx and Jounce unanimously recommended a
business combination of the two companies via an all share merger transaction
(the "Business Combination"), which is expected to complete during the second
quarter of 2023 subject to necessary regulatory and shareholder approvals.
Further updates will be made as and when appropriate.
For further information, please contact:
Redx Pharma Plc T: +44 (0)1625 469 918
UK Headquarters
Caitlin Pearson Head of Communications
ir@redxpharma.com (mailto:ir@redxpharma.com)
Lisa Anson, Chief Executive Officer
US Office
Peter Collum, Chief Financial Officer
Centerview Partners UK LLP (Financial Adviser to Redx) T: +44 (0) 20 7409 9700
Richard Girling/ Hadleigh Beals/ Alex Elias
SPARK Advisory Partners (Nominated Adviser) T: +44 (0)203 368 3550
Matt Davis/ Adam Dawes
WG Partners LLP (Joint Broker) T: +44 (0)203 705 9330
David Wilson/ Claes Spång
Panmure Gordon (UK) Limited (Joint Broker) T: +44 (0)207 886 2500
Rupert Dearden/ Freddy Crossley/ Emma Earl
FTI Consulting (Financial Communications Adviser) T: +44 (0)203 727 1000
Simon Conway/ Ciara Martin
About Redx Pharma Plc
Redx Pharma (AIM: REDX) is a clinical-stage biotechnology company focused on
the discovery and development of novel, small molecule, highly targeted
therapeutics for the treatment of cancer and fibrotic disease and the emerging
area of cancer-associated fibrosis, aiming initially to progress them to
clinical proof of concept before evaluating options for further development
and potential value creation. The Company's lead fibrosis product candidate,
the selective ROCK2 inhibitor RXC007, is in development for interstitial lung
disease and commenced a Phase 2a trial for idiopathic pulmonary fibrosis (IPF)
in October 2022, with topline data expected in Q1 2024. Redx's lead oncology
product candidate, the Porcupine inhibitor RXC004, being developed as a
targeted treatment for Wnt-ligand dependent cancers, is expected to report
both monotherapy and combination with anti-PD-1 Phase 2 data during 2023.
Redx's third drug candidate, RXC008, a GI-targeted ROCK inhibitor for the
treatment of fibrostenotic Crohn's disease, is progressing towards a CTA/IND
application at the end of 2023.
The Company has a strong track record of discovering new drug candidates
through its core strengths in medicinal chemistry and translational science,
enabling the Company to discover and develop differentiated therapeutics
against biologically or clinically validated targets. The Company's
accomplishments are evidenced not only by its two wholly-owned clinical-stage
product candidates and rapidly expanding pipeline, but also by its strategic
transactions, including the sale of pirtobrutinib (RXC005, LOXO-305), a
non-covalent (reversible) BTK inhibitor now approved by the US FDA for adult
patients with mantle cell lymphoma previously treated with a covalent BTK
inhibitor, and AZD5055/RXC006, a Porcupine inhibitor targeting fibrotic
diseases including IPF, which AstraZeneca is progressing in a Phase 1 clinical
study. In addition, Redx has forged collaborations with Jazz Pharmaceuticals,
which includes JZP815, a pan-RAF inhibitor developed by Redx which Jazz is now
progressing through Phase 1 clinical studies, and an early stage oncology
research collaboration.
To subscribe to Email Alerts from Redx, please visit:
www.redxpharma.com/investor-centre/email-alerts/
(http://www.redxpharma.com/investor-centre/email-alerts/)
Important Notices
Centerview Partners UK LLP ("Centerview"), which is authorised and regulated
in the United Kingdom by the Financial Conduct Authority (the "FCA"), is
acting exclusively as financial adviser to Redx and no one else in connection
with the Business Combination and will not be responsible to anyone other than
Redx for providing the protections afforded to its clients or for providing
advice in relation to the Business Combination, the contents of this
Announcement or any other matters referred to in this Announcement. Neither
Centerview nor any of its affiliates, nor any of Centerview's and such
affiliates' respective members, directors, officers, controlling persons or
employees owes or accepts any duty, liability or responsibility whatsoever
(whether direct or indirect, consequential, whether in contract, in tort, in
delict, under statute or otherwise) to any person who is not a client of
Centerview in connection with this Announcement, any statement contained
herein, the Business Combination or otherwise.
SPARK Advisory Partners Limited ("SPARK"), which is authorised and regulated
in the United Kingdom by the FCA is acting as nominated adviser to Redx and
for no one else in connection with the Business Combination and other matters
referred to in this Announcement and will not be responsible to anyone other
than Redx for providing the protections afforded to its clients or for
providing advice in relation to the Business Combination, the contents of this
Announcement or any other matters referred to in this Announcement. Neither
SPARK nor any of its affiliates, directors or employees owes or accepts any
duty, liability or responsibility whatsoever (whether direct or indirect,
consequential, whether in contract, in tort, in delict, under statute or
otherwise) to any person who is not a client of SPARK in connection with this
Announcement, any statement contained herein, the Business Combination or
otherwise.-
WG Partners LLP ("WG Partners"), which is authorised and regulated in the
United Kingdom by the FCA is acting as Corporate Broker to Redx and for no one
else in connection with the Business Combination and other matters referred to
in this Announcement and will not be responsible to anyone other than Redx for
providing the protections afforded to its clients or for providing advice in
relation to the Business Combination, the contents of this Announcement or any
other matters referred to in this Announcement. Neither WG Partners nor any of
its affiliates, members, directors or employees owes or accepts any duty,
liability or responsibility whatsoever (whether direct or indirect,
consequential, whether in contract, in tort, in delict, under statute or
otherwise) to any person who is not a client of WG Partners in connection with
this Announcement, any statement contained herein, the Business Combination or
otherwise.
Panmure Gordon (UK) Limited ("Panmure Gordon"), which is authorised and
regulated by the FCA in the United Kingdom is acting as Corporate Broker to
Redx and for no one else in connection with the Business Combination and other
matters referred to in this Announcement and will not be responsible to anyone
other than Redx for providing the protections afforded to its clients or for
providing advice in relation to the Business Combination, the contents of this
Announcement or any other matters referred to in this Announcement. Neither
Panmure Gordon nor any of its affiliates, directors or employees owes or
accepts any duty, liability or responsibility whatsoever (whether direct or
indirect, consequential, whether in contract, in tort, in delict, under
statute or otherwise) to any person who is not a client of Panmure Gordon in
connection with this Announcement, any statement contained herein, the
Business Combination or otherwise.
The release, publication or distribution of this Announcement in or into
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Persons who are not resident in the United Kingdom or who are subject to other
jurisdictions should inform themselves of, and observe, any applicable
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does not constitute, or form part of, an offer, invitation or the solicitation
of an offer or invitation to purchase, otherwise acquire, subscribe for, sell
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