** Shares of Regulus Therapeutics RGLS.O rise 65.2% to
$2.28 premarket
** Co says that its therapy for autosomal dominant
polycystic kidney disease (ADPKD) in an early-stage trial showed
a response in patients based on levels of polycystins in urine
** RGLS says three patients with the highest increases in
polycystins also had reductions in total kidney cyst volume
** ADPKD is the most common form of polycystic kidney
disease, which causes numerous cysts to grow in the kidneys, and
may lead to kidney failure
** Up to last close, stock up 9.5% in the last 12 months
(Reporting by Puyaan Singh)
((Puyaan.Singh@thomsonreuters.com;))