** Shares of Revance Therapeutics Inc RVNC.O surge 44% to
$28.39; set for their biggest daily pct rise on record, if gains
hold
** Stock among top gainers on Nasdaq Biotechnology index
.NBI
** Co reports preliminary Q4 results; expects revenue from
an early experience program of its anti-wrinkle injection
Daxxify to be between $10.5 mln-$11.5 mln in the quarter
** U.S. FDA approved the injection in September, setting up
a challenger for market leader AbbVie's ABBV.N Botox
** Brokerage Cowen and Co says RVNC's Q4 update marks "a
stunning initial performance and sets a strong foundation for
the upcoming broader Daxxify introduction" given that Wall
Street expectations for the injection were minimal, and the
launch only initiated in Dec. 2022
** Co expects full commercial launch of Daxxify to begin in
late Q1/early Q2 of 2023
** "Our consultants continue to believe Daxxify could
potentially completely disrupt what has long been a
Botox-dominated undifferentiated market" - Cowen
** RVNC shares gained ~13% in 2022, compared with ~11%
decline in Nasdaq Biotechnology index in the same period
(Reporting by Raghav Mahobe)
((Raghav.Mahobe@thomsonreuters.com;))