** Shares of biotech firm Revolution Medicines RVMD.O jump 37% to $133 premarket
** Company says its experimental pill daraxonrasib in a late-stage study met main goals of improving how long patients with pancreatic cancer lived overall and how long the disease stayed under control
** Patients on the drug showed median overall survival of 13.2 months vs 6.7 months on chemotherapy in the trial, which enrolled participants whose cancer worsened after prior treatment
** Daraxonrasib targets RAS mutations, which drive tumor growth in more than 90% of pancreatic cancer cases
** The drug was generally well tolerated, with no new safety concerns - company
** RVMD plans to seek regulatory approval; drug has FDA breakthrough and orphan designations
** As of last close, shares up ~21% this year
(Reporting by Sahil Pandey in Bengaluru)
((Sahil.Pandey@thomsonreuters.com))