(Updates)
** Shares of Sage Therapeutics SAGE.O fall 20.03% to
$12.60 premarket
** Stock among top pct. losers across U.S. exchanges before
the bell
** Co says its experimental drug Dalzanemdor failed to meet
its main goal in a mid-stage study in people with mild cognitive
impairment in Parkinson's Disease
** Based on the result, the company does not plan any
further development of the drug for Parkinson's Disease
** The drug did not show statistically significant
differences versus placebo on a testing score that measures the
cognitive ability
** The study enrolled a total of 86 participants and was
designed to evaluate the safety and efficacy of Dalzanemdor
dosed over 6 weeks
** Parkinson's disease is a brain condition that causes
problems with movement, mental health, sleep, pain and other
health issues
** Up to last close, stock down ~28% YTD
(Reporting by Sriparna Roy in Bengaluru)
((Sriparna.Roy@thomsonreuters.com;))