** Shares of Sage Therapeutics SAGE.O fall 19% to $10.60
premarket
** Co, partner Biogen's BIIB.O oral experimental drug,
SAGE-324, to treat essential tremors failed in a mid-stage study
** Co, BIIB do not plan to develop the drug further but may
consider it for other potential conditions
** Essential tremor is a condition that affects the nervous
system and causes involuntary and rhythmic shaking
** Treatment with SAGE-BIIB's drug did not result in
statistically significant changes in tremor severity for upper
limbs as measured on a commonly used rating scale
** Mizuho analysts said that the trial failure could weaken
SAGE and BIIB's collaboration
** As of last close, SAGE down ~40% YTD
(Reporting by Bhanvi Satija in Bengaluru; Editing by Shailesh
Kuber)
((Bhanvi.Satija@thomsonreuters.com; Outside U.S. +91
9873062788;))