(Updates)
** Shares of drug developer Sagimet Biosciences SGMT.O
more than double to record high of $16
** Co says its experimental fatty liver disease drug met the
main goal of a mid-stage trial
** The experimental drug called denifanstat helped in
significantly reducing symptoms of the disease including fat
accumulation, inflammation, and fibrosis compared to placebo
** Co says safety profile of the drug observed in study
supports further development
** Most commonly reported adverse events were eye disorders,
gastrointestinal disorders and skin disorders and were all mild
to moderate in nature - SGMT
** Co says 19.6% patients in the treatment group who
experienced treatment-related side effects stopped taking the
drug compared to 5.4% patients in the placebo group
** SGMT to hold a meeting with the U.S. FDA to start
late-stage study of the drug in second half of 2024
** Stock has fallen 57.1% since its Nasdaq debut in July
2023
(Reporting by Sneha S K)
((Sneha.SK@thomsonreuters.com;))