** Shares of gene therapy developer Sana Biotechnology Inc
SANA.O down 4.1% to $4.52
** Co late on Tuesday said it is optimizing its pipeline and
will discontinue internal investment in its program, SC187, for
heart muscle cells cardiomyocytes
** Co also said it will cut 15% of its workforce
** SANA will focus on its cancer program, SC263 and expects
to file marketing application to the U.S. FDA by 2023
** Brokerage BofA Global Research cuts price objective to
$13 from $15, says changes make strategic sense and will help co
to focus that could engage investors and "bolster" stock price
** SANA has a cash runway until 2025 which should allow it
to transition into a clinical stage company - BofA
** Co had $511.6 million in cash and cash equivalents as of
Sept. 30
** Including session losses, stock had fallen ~71% YTD vs a
~10% decline in the Nasdaq Biotechnology index .NBI
(Reporting by Sriparna Roy)
((Sriparna.roy@thomsonreuters.com))