REG - Sareum Holdings PLC - US patent allowance

Sareum HoldingsAnnouncement

02/09/2024 07:00

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RNS Number : 4191C  Sareum Holdings PLC  02 September 2024

Sareum Holdings plc

("Sareum" or the "Company")

US patent allowance for its lead programme SDC-1801

-      Notice of Allowance from US Patent and Trademark Office received

Cambridge, UK, 2 September 2024 - Sareum Holdings plc (AIM: SAR), a
clinical-stage biotechnology company developing next-generation kinase
inhibitors for autoimmune disease and cancer, is pleased to announce that it
has received a Notice of Allowance from the US Patent and Trademark Office
(USPTO) for a patent on SDC-1801, a dual TYK2/JAK1 kinase inhibitor being
developed as a potential new therapeutic for a range of autoimmune diseases.

The US patent, application number US2021387981, will offer substantial
protection on the chemical structure of SDC-1801 and an analogue, their use in
treating inflammatory diseases and in certain methods of their chemical
synthesis.

Sareum has now secured patent coverage in the major territories, following
patent approvals by the European Patent Office, China National Intellectual
Property Administration and Japan Patent Office for the same protections. The
Company expects the US patent to be granted by the end of 2024, subject to the
fulfilment of certain formalities with the USPTO.

Dr John Reader, Sareum's Chief Scientific Officer, commented: "We are pleased
to extend the patent protection for SDC-1801 on the back of the encouraging
data from our Phase 1a trial, indicating our inhibitor could confer
significant advantages over other TYK2/JAK1 kinase inhibitors. We remain
motivated in progressing SDC-1801 through clinical development to develop new
therapeutics for autoimmune diseases and cancers."

- Ends -

For further information, please contact:

 Sareum Holdings plc

 Stephen Parker, Executive Chairman               01223 497700

                                                  ir@sareum.co.uk

 Strand Hanson Limited (Nominated Adviser)

 James Dance / James Bellman                      020 7409 3494

 Hybridan LLP (Corporate Broker)

 Claire Noyce                                     020 3764 2341

 ICR Consilium (Financial PR)

 Jessica Hodgson / Davide Salvi / Kumail Waljee   0203 709 5700

 

About Sareum

Sareum Holdings (AIM:SAR) is a clinical-stage biotechnology company developing
next generation kinase inhibitors for autoimmune disease and cancer.

The Company is focused on developing next generation small molecules which
modify the activity of the JAK kinase family and have best-in-class potential.
Its lead candidate, SDC-1801, simultaneously inhibits TYK2 and JAK1. SDC-1801
is a potential treatment for a range of autoimmune diseases and has entered
Phase 1a/b clinical development with an initial focus on psoriasis.

Sareum is also developing SDC-1802, a TYK2/JAK1 inhibitor with a potential
application for cancer immunotherapy.

Sareum Holdings plc is based in Cambridge, UK, and is listed on the AIM market
of the London Stock Exchange, trading under the ticker SAR. For further
information, please visit the Company's website at www.sareum.com
(http://www.sareum.com)

 

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