REG - Scancell Holdings - Half-year Financial Report
Today 07:00
For best results when printing this announcement, please click on link below:
https://newsfile.refinitiv.com/getnewsfile/v1/story?guid=urn:newsml:reuters.com:20260129:nRSc8035Qa&default-theme=true
RNS Number : 8035Q Scancell Holdings Plc 29 January 2026
29 January 2026
Scancell Holdings plc
("Scancell", the "Company" or the "Group")
Interim Results for the six months ended 31 October 2025
Scancell Holdings plc (AIM: SCLP), the developer of ImmunoBody(®) and
Moditope(®) active immunotherapies to treat cancer, today announces a
business update and provides its unaudited financial results for the six-month
period to 31 October 2025.
Highlights (including post period)
DNA ImmunoBody (®) iSCIB1+ (SCOPE trial):
· iSCIB1+, the lead product from Scancell's DNA ImmunoBody(®)
platform, demonstrated potentially best-in-class efficacy and durability, and
strong Progression Free Survival (PFS) with checkpoint inhibitors (CPIs) in a
Phase 2 trial in advanced melanoma:
o 74% PFS at 16 months for iSCIB1+ with the double CPIs of nivolumab and
ipilimumab
o A 24%-point improvement in PFS over real-world standard of care (SoC) and
historic controls
o Strong PFS data continues to be collected across key subgroups
o Selection marker identified to enrich the phase 3 trial for responders.
· The U.S. Food and Drug Administration (FDA) cleared an Investigational
New Drug (IND) application for a registrational Phase 3 trial of iSCIB1+
ImmunoBody(®) in advanced melanoma, with PFS as the agreed surrogate
endpoint.
· Completed 140-patient SCOPE Phase 2 study evaluating ImmunoBody(®)
immunotherapies (SCIB1 and iSCIB1+) in combination with nivolumab plus
ipilimumab in previously untreated unresectable stage IIIB/IV melanoma.
· Continued evaluation of all financing options, including partnering
discussions, for the Phase 3 development of iSCIB1+ for the treatment of
advanced melanoma.
· A global Phase 3 registrational study planned to commence in 2026,
with potential read-out and commercialisation in 2029.
Moditope(®) Modi-1 (ModiFY trial):
· Modi-1, a citrullinated peptide off-the-shelf vaccine, is showing
early promise in a Phase 2 study for the treatment of squamous cell cancer of
head and neck (SSCHN) and renal cell carcinoma (RCC).
· The study will assess whether Modi-1 in combination with CPIs
improves outcomes in these indications against the current SoC.
· Data readouts for Modi-1 in SSCHN and RCC anticipated in H1 2026.
Antibodies:
· GlyMab Therapeutics Limited was incorporated as a wholly owned
subsidiary with the intention to hold antibody assets and platforms providing
focused resources and strategic optionality for further development.
· Developability studies initiated and positive scientific advice
received from the FDA and MHRA for the lead antibody product, SC134, which has
best-in-class potential for the treatment of small cell lung cancer (SCLC)
following early in vivo data.
· Development of antibodies partnered with Genmab under our two license
agreements remains on track with milestones anticipated in 2026.
Financial:
· Operating loss for the six months ended 31 October 2025 of £8.9
million (six months ended 31 October 2024: £10.5 million).
· The Group cash balance at 31 October 2025 was £8.6 million (30
April 2025: £16.9 million), enhanced post period with the receipt of £3.0
million of R&D tax credits.
· Cash runway to H2 2026, beyond near-term clinical and regulatory
milestones and with further upside opportunities.
Outlook
Key near-term milestones include:
· Submission of iSCIB1+ Phase 3 applications to the MHRA and other
agencies
· iSCIB1+ Phase 3 trial commencement in 2026
· Further iSCIB1+ PFS data from SCOPE trial around mid-2026
· Modi-1 data for RCC and SSHN with double CPIs in H1 2026
· Continued antibody discovery and business development for GlyMab
Therapeutics.
Phil L'Huillier, Chief Executive Officer, Scancell, commented: "iSCIB1+ has
demonstrated strong potential to redefine standard of care for advanced
melanoma, and we are proud to advance this new off-the-shelf treatment for
cancer patients through clinical development to address what remains a
significant unmet medical need. Based on the strong Phase 2 SCOPE data, we
accelerated our plans for a global registrational Phase 3 study and have now
received a rapid clearance for our IND from the US FDA as well as positive
feedback from other regulators including EMA and MHRA. We are well positioned
to initiate the study in 2026.
We continue our partnering discussions on iSCIB1+ and the ImmunoBody(®)
platform with the regulatory feedback in hand and will evaluate all financing
options with the dual focus on progressing the Phase 3 trial in a timely
manner and optimising shareholder value. There is continuing partnering
interest in our lead antibody, SC134, and our other GlyMab(®) candidates
through which we expect to generate further shareholder value in the coming
year, while we will also explore partnering opportunities for Moditope(®)
following new Modi-1 Phase 2 data expected in H1 2026."
Phil L'Huillier, Chief Executive Officer and Sath Nirmalananthan, Chief
Financial Officer, will also host a live webcast for analysts and investors
today at 14:00 GMT. If you would like to join the webcast, please follow this
link:
Interim Financial Results for the six months ending 31 October 2025 |
SparkLive | LSEG
(https://sparklive.lseg.com/ScancellHoldings/events/0e324d6f-4f3a-43b6-8598-82b26bbd6862/interim-financial-results-for-the-six-months-ending-31-october-2025)
A replay of the webcast will be made available shortly afterwards.
A full copy of the announcement can be found on the Scancell website:
www.scancell.co.uk (http://www.scancell.co.uk)
This announcement contains inside information for the purposes of Article 7 of
Regulation (EU) 596/2014 (MAR).
For further information, please contact:
Scancell Holdings plc +44 (0) 20 3709 5700
Phil L'Huillier, CEO
Sath Nirmalananthan, CFO
Dr Jean-Michel Cosséry, Non-Executive Chairman
Panmure Liberum (Nominated Adviser and Joint Broker) +44 (0) 20 7886 2500
Emma Earl, Will Goode, Mark Rogers (Corporate Finance)
Rupert Dearden (Corporate Broking)
WG Partners LLP (Joint Broker) +44 (0) 20 3705 9330
David Wilson, Claes Spang
Investor and media relations +44 (0) 20 7483 284853
Mary-Ann Chang MaryAnnChang@scancell.co.uk (mailto:MaryAnnChang@scancell.co.uk)
About Scancell
Scancell (LSE:SCLP; www.scancell.co.uk (http://www.scancell.co.uk) ) is a
clinical stage biotechnology company developing targeted off-the-shelf active
immunotherapies, to generate safe and long-lasting tumour-specific immunity
for a cancer-free future. iSCIB1+, the lead product from their DNA
ImmunoBody(®) platform has demonstrated safe, durable and clinically
meaningful benefit as a monotherapy as well as additional benefit when
combined with checkpoint therapies in a Phase 2 trial in melanoma. Modi-1, the
lead peptide immunotherapy from their Moditope(®) platform, is being
investigated in a Phase 2 study in a broad range of solid tumours. In
addition, Scancell's wholly owned subsidiary, GlyMab Therapeutics Ltd., has
been established with the intention to hold and develop an exciting
early-stage pipeline of high affinity GlyMab(®) antibodies targeting tumour
specific glycans, two of which already have been licensed and are being
developed by Genmab A/S, an international biotechnology company and global
leader in the antibody therapeutics space.
CHIEF EXECUTIVE OFFICER'S STATEMENT
I am pleased to report the interim results for the six-month period ended 31
October 2025 and provide a business update. We recently submitted our Phase 3
IND to the US Food and Drug Administration (FDA) for our lead product, iSCIB1+
in combination with checkpoint inhibitors (CPIs) for the treatment of advanced
melanoma. This submission, which has recently received clearance, and other
regulatory progress followed strong iSCIB1+ results and the completion of our
Phase 2 study objectives. Subject to financing, we anticipate initiating the
global registrational Phase 3 trial later in 2026.
Set out below is a summary of progress that has been made with our lead cancer
therapies and antibodies. Full details of the platforms and other assets are
detailed in the Company's 2025 Annual Report and website (www.scancell.co.uk
(http://www.scancell.co.uk/) ).
DNA ImmunoBody(®) iSCIB1+
Our lead candidate, iSCIB1+ is a non-personalised DNA active immunotherapy
from the Company's DNA ImmunoBody(®) platform. It has been evaluated in the
Phase 2 SCOPE trial, in combination with CPIs for the first-line treatment for
advanced unresectable melanoma and will be further evaluated in a Phase 3
study following our recent IND clearance. The doublet therapy of ipilimumab
(Yervoy(®)) and nivolumab (Opdivo(®)) is the preferred treatment option in
the first line setting for unresectable melanoma. The addition of iSCIB1+ to
this treatment option has the potential to improve patient outcomes and set
the new standard for first-line treatment.
iSCIB1+ is our most advanced therapy developed using the Company's
ImmunoBody(®) technology. It has melanoma-specific epitopes and can address
approximately 80% of the patient population. Combined with its increased
potency and extended patent duration, it represents a strong investment
opportunity. We are actively engaged in discussions with potential partners
and assessing all financing options for the next stage of development.
In December 2025, the Company announced further positive data from its third
cohort of the SCOPE trial, showing progression free survival (PFS) of 74% at
16 months in patients with selected human leukocyte antigen (HLA) alleles
("the target HLA population"). This compares favourably to PFS reported with
ipilimumab plus nivolumab alone of 50% at 11.5 months ( 1 ). The favourable
PFS remains consistent across key subgroups analysed including PD-L1 low, BRAF
Wildtype and prior checkpoint inhibitor exposure, who might be expected to
have worse outcomes. Cohort 3 comprised a total of 50 patients of which 39
were in the target HLA population, 10 outside the target HLA population and
one was non-evaluable due to active brain metastases. Data in this cohort from
the non-target population support the use of HLA as a biomarker in our
registrational trial, with PFS of 20% at 14 months and overall response rate
of 20%, albeit in a small number of patients.
Overall response rate for the target population in Cohort 3 was 56%, with a
disease control rate of 79%. iSCIB1+ specific T cell responses correlated
positively with clinical benefit, seen in 72% of patients mounting a T-cell
response to both GP100 and TRP2 epitopes, thereby overcoming immune escape. A
memory T-cell response phenotype was also characterised in these patients.
Early overall survival (OS) data is most advanced for our superseded therapy,
SCIB1, which to date has shown a 14% improvement, namely 77% at 24 months,
over SoC.
Following the data and positive scientific advice outcomes from the FDA, the
European Medicines Agency (EMA) and the Medicines and UK Healthcare products
Regulatory Agency (MHRA), we received FDA clearance for our IND in January
2025. We are well positioned to take further steps to proceed with the Phase 3
trial in the coming months.
( 1 ) Ipilimumab and Nivolumab in Checkmate 067
Modi-1 (ModiFY study)
Modi-1, a citrullinated peptide off-the-shelf therapy, is the lead candidate
from Scancell's Moditope(®) platform. It has demonstrated potent T-cell
responses and strong anti-tumour clinical activity in several solid cancer
models tumour types, including squamous cell cancer of head and neck (SSCHN)
and renal cell carcinoma (RCC). Early monotherapy data showed good safety and
ability to induce stable disease for long periods in patients, and we have
also developed robust and scalable Modi-1 manufacturing, which is further
supported by a strong patent portfolio.
Our Phase 2 ModiFY study has shown promising early signs and is currently
assessing whether our most advanced formulation of Modi-1 with CPIs improves
outcomes in SSCHN and RCC against the current SoC. Data readouts are scheduled
for the first half of this year.
GlyMab(®)
The GlyMab(®) platform has generated antibodies which bind to sugar motifs,
rather than peptide epitopes, found on the surface of glycosylated proteins
and lipids expressed by cancer cells. Our lead GlyMab(®) candidate, SC134,
has generated strong in vivo data and commercial interest. Positive scientific
advice has been received from the FDA and MHRA to support initiation of a
Phase 1/2 clinical trial. Scancell also has two active revenue-generating
collaborations with Genmab A/S for other candidates under which it expects to
receive further milestone payments.
In June 2025, Scancell incorporated Glymab Therapeutics Limited as a wholly
owned subsidiary with the aim of facilitating further financing and partners
for the GlyMab(®) platform. In addition to the internal progress made to
facilitate potential business transactions, we remain actively engaged with
potential partners externally.
Financial Review
Consolidated Statement of Comprehensive Loss
The six-month periods ended 31 October 2025 and 2024 are referred to as "2025"
and "2024" in this section.
The Group recorded an operating loss for the six-month period ended 31 October
2025 of £8.9 million (2024: loss of £10.5 million).
Research and development ("R&D") expenditure decreased by £1.9 million to
£6.1 million in 2025 (2024: £8.0 million) primarily due to higher
manufacturing costs in 2024 from the development and completion of a scaled
GMP iSCIB1+ clinical trial batch.
Administrative expenses were largely consistent at £2.7 million (2024: £2.5
million), with the £0.2 million increase driven by a higher administrative
component of non-cash share-based payment costs in 2025 following option
awards to directors in February 2025.
Further items for the six-month period to 31 October 2025 included:
· Interest expense of £1.0 million (2024: £0.8 million)
reflecting a notional rate of interest on the convertible loan notes issued by
the Group.
· Finance income of £2.9 million (2024: expense of £4.5 million)
arising from non-cash movements in the fair value of the derivative
liabilities, which represent the value of the loan note conversion options.
· An estimate of cash R&D tax credits receivable relating to
the six month-period of £1.1 million (2024: £1.3 million).
The prior six-month period to 31 October 2024 also included a net gain of
£1.8 million following substantial modification of the convertible loan notes
in July 2024.
The overall loss after tax for 2025 was £5.7 million (2024: £12.5 million).
The variance to the prior period was driven by the non-cash items relating to
convertible notes and the reduction in R&D expenditure described above.
Consolidated Statement of Financial Position
At 31 October 2025, net liabilities of the Group amounted to £8.4 million (30
April 2025: £3.8 million) and it held cash of £8.6 million (30 April 2025:
£16.9 million). R&D tax credits of £3.0 million relating to the year
ended 30 April 2025 were subsequently received in December 2025.
Following early partial redemption of £1.0 million of convertible loan notes
in September 2025, a total of £18.2 million notes remain outstanding
(recorded as £15.9 million on an amortised cost basis in the Consolidated
Statement of Financial Position at 31 October 2025). These notes are due to be
repaid in August 2027 (£1.75 million) and November 2027 (£16.45 million)
unless converted by Redmile LLC into ordinary shares in the Company.
Derivative liabilities associated with the above notes totalling £4.4 million
(30 April 2025: £7.5 million) represented the fair value of the conversion
feature of the convertible loan notes at the respective period ends. This
non-cash decrease in liabilities reflected reductions in Scancell's share
price, share price volatility, the number of shares convertible following the
early partial redemption, and in the time to maturity of the outstanding
notes.
Consolidated Cash Flow Statement
The £8.3 million reduction in cash and cash equivalents from £16.9 million
at 30 April 2025 to £8.6 million at 31 October 2025 resulted from cash used
in operations of £7.2 million (2024: £7.8 million), and the convertible loan
repayment of £1.0 million (2024: repayment of £0.5 million).
Phillip L'Huillier
Chief Executive
Officer
Scancell Holdings plc
Consolidated Statement of Comprehensive Loss
for the six-month period to 31 October 2025
Unaudited Unaudited Audited
6 months 6 months Year to
31/10/2025 31/10/2024 30/04/2025
Note £'000 £'000 £'000
Revenue - - 4,711
Cost of sales - - (238)
Gross profit - - 4,473
R&D expenses (6,145) (8,043) (14,686)
Administrative expenses (2,747) (2,502) (4,788)
OPERATING LOSS (8,892) (10,545) (15,001)
Interest receivable and similar income 200 159 336
Interest expense (977) (793) (1,717)
Finance income / (expense) relating to revaluation of derivative liability 3 2,881 (4,474) (737)
Gain on substantial modification of convertible loan notes 3 - 1,816 1,816
Loss on early settlement of convertible loan notes (20) - -
Loss and total comprehensive loss before tax (6,808) (13,837) (15,303)
Taxation 4 1,066 1,334 3,031
LOSS FOR THE PERIOD (5,742) (12,503) (12,272)
LOSS PER ORDINARY SHARE (PENCE)
Basic 2 (0.55)p (1.35)p (1.26)p
Diluted 2 (0.64)p (1.35)p (1.26)p
Scancell Holdings plc
Consolidated Statement of Financial Position
as at 31 October 2025
Unaudited Unaudited Audited
31/10/2025 31/10/2024 30/04/2025
£'000 £'000 £'000
ASSETS Note
Non-current assets
Intangible assets 1,618 1,514 1,619
Tangible fixed assets 198 578 372
Right-of-use assets 293 672 475
Total non-current assets 2,109 2,764 2,466
Current assets
Trade and other receivables 533 608 631
Taxation receivable 4 4,161 4,130 3,099
Cash and cash equivalents 8,574 9,103 16,894
Total current assets 13,268 13,841 20,624
TOTAL ASSETS 15,377 16,605 23,090
LIABILITIES
Non-current liabilities
Lease liabilities - (278) (123)
Total non-current liabilities - (278) (123)
Current liabilities
Deferred revenue - (782) -
Convertible notes - loan liabilities 3 (15,862) (14,844) (15,753)
Derivative liabilities 3 (4,421) (11,217) (7,480)
Trade and other payables (3,146) (4,544) (3,178)
Lease liabilities (320) (440) (391)
Total current liabilities (23,749) (31,827) (26,802)
TOTAL LIABILITIES (23,749) (32,105) (26,925)
NET LIABILITIES (8,372) (15,500) (3,835)
EQUITY
Called up share capital 1,038 930 1,037
Share premium account 82,483 71,954 82,403
Merger reserve 5,043 5,043 5,043
Share option reserve 5,265 3,263 4,141
Retained losses (102,201) (96,690) (96,459)
Total Equity (8,372) (15,500) (3,835)
Scancell Holdings plc
Consolidated Statement of Changes in Equity
for the six-month period to 31 October 2025
Share
Share Share option Merger Retained Total
capital premium reserve reserve earnings Equity
£'000 £'000 £'000 £'000 £'000 £'000
Unaudited Unaudited Unaudited Unaudited Unaudited Unaudited
At 1 May 2025 1,037 82,403 4,141 5,043 (96,459) (3,835)
Loss for the period - - - - (5,742) (5,742)
Transactions with owners
Share option exercises 1 80 - - - 81
Share option costs - - 1,124 - - 1,124
At 31 October 2025 1,038 82,483 5,265 5,043 (102,201) (8,372)
At 1 May 2024 929 71,927 2,783 5,043 (84,187) (3,505)
Loss for the period - - - - (12,503) (12,503)
Transactions with owners
Share option exercises 1 27 - - - 28
Share option costs - - 480 - - 480
At 31 October 2024 930 71,954 3,263 5,043 (96,690) (15,500)
Audited Audited Audited Audited Audited Audited
At 1 May 2024 929 71,927 2,783 5,043 (84,187) (3,505)
Loss for the year - - - - (12,272) (12,272)
Transactions with owners
Share placing and open offer, 107 10,449 - - - 10,556
net of issuance costs
Share option exercises 1 27 - - - 28
Share option costs - - 1,358 - - 1,358
At 30 April 2025 1,037 82,403 4,141 5,043 (96,459) (3,835)
Scancell Holdings plc
Consolidated Cash Flow Statement
for the six-month period to 31 October 2025
Unaudited Unaudited Audited
6 months 6 months Year to
31/10/2025 31/10/2024 30/04/2025
£'000 £'000 £'000
Cash flows from operating activities
Loss before tax for the period (6,808) (13,837) (15,303)
Adjustments for:
Interest receivable and similar income (200) (159) (336)
Interest expense 977 793 1,717
Gain on substantial modification of convertible loan notes - (1,816) (1,816)
Loss on early settlement of convertible loan notes 20 - -
Finance (gain) / expense relating to derivative liability revaluation (Note 3) (2,881) 4,474 737
Share based payment charge (Note 5) 1,124 480 1,358
Depreciation of non-current assets 377 479 879
Other items 6 60 29
Cash used in operations before changes in working capital (7,385) (9,526) (12,735)
Decrease in trade and other receivables 98 770 747
Increase/(decrease) in deferred revenue and other operating payables 64 910 (15)
Cash used in operations (7,223) (7,846) (12,003)
Tax credits received 3 2,876 5,604
Net cash used in operating activities (7,220) (4,970) (6,399)
Cash flows from investing activities
Purchase of intangible assets (93) (197) (1,525)
Purchase of tangible fixed assets - - (14)
Interest received 200 159 336
Net cash from / (used in) investing activities 107 (38) (1,203)
Financing activities
Proceeds from issuance on placing and open offer - - 11,254
Costs of share issuances - - (698)
Proceeds from share option exercises 81 28 28
Convertible loan note repayments (Note 3) (1,000) (450) (450)
Interest paid (61) (28) (43)
Lease principal payments (214) (196) (401)
Net cash (used in) / from financing activities (1,194) (646) 9,690
Net (decrease) / increase in cash and cash equivalents (8,307) (5,654) 2,088
Net foreign exchange difference on cash held (13) (60) (11)
Cash and cash equivalents at beginning of the year 16,894 14,817 14,817
Cash and cash equivalents at end of the period 8,574 9,103 16,894
Scancell Holdings plc
Notes to the Interim Financial Statements
for the six-month period to 31 October 2025
1 Basis of preparation
This interim report for the six-month period to 31 October 2025 is unaudited
and was approved by the Directors on 28 January 2026. The financial
information contained in the interim report is consistent with the accounting
policies set out in the annual report and financial statements for the year
ended 30 April 2025 and reflects policies expected to apply to the Group's
financial statements for the year ended 30 April 2026. As permitted, this
interim report has been prepared in accordance with AIM Rule 18 and not in
accordance with IAS 34 "Interim Financial Reporting", and therefore, it is not
fully in compliance with UK adopted international accounting standards.
The financial information for the full preceding year is based on the
statutory accounts for the year ended 30 April 2025. The report of the auditor
on the 30 April 2025 statutory financial statements was unqualified and did
not contain a statement under Section 498(2) or Section 498(3) of the
Companies Act 2006, but did draw attention to the Group's ability to continue
as a going concern by way of a material uncertainty paragraph.
2 Loss per share
The earnings and weighted average number of ordinary shares used in the
calculation of basic and diluted loss per share are set out in the tables
below.
Basic loss per share
6 months to 6 months to Year ended
31/10/2025 31/10/2024 30/04/2025
£'000 £'000 £'000
Loss for the period (5,742) (12,503) (12,272)
Number Number Number
Weighted average number of shares used in basic loss per share
1,037,406,403 929,404,542 970,318,493
Basic loss per share (0.55)p (1.35)p (1.26)p
Diluted loss per share
6 months to 6 months to Year ended
31/10/2025 31/10/2024 30/04/2025
£'000 £'000 £'000
Loss for the period (5,742) (12,503) (12,272)
Adjustment for the effect of convertible loan notes (1,894) - -
Adjusted loss used in the calculation of diluted loss per share (7,636) (12,503) (12,272)
Number Number Number
Basic weighted average number of ordinary shares
1,037,406,403 929,404,542 970,318,493
Adjustment for convertible loan notes with dilutive effect
162,004,835 - -
Diluted weighted average number of ordinary shares
1,199,411,238 929,404,542 970,318,493
Diluted loss per share (0.64)p (1.35)p (1.26)p
Convertible loan notes in the 6 months to 31 October 2025 had a dilutive
effect on loss per share. Diluted loss per share assumes that the notes had
been converted at the start of the year, which would have resulted in an
increase in loss for this period following the removal of post-tax derivative
finance income and loan interest expense. Convertible loan notes in the six
months ended 31 October 2024 and 30 April 2025 and the effect of share options
in all periods have been excluded from the calculation of diluted loss per
share in all periods since these would have the effect of reducing the loss
per share.
At 31 October 2025, the issued share capital amounted to 1,037,781,403
ordinary shares.
3 Convertible loan note liabilities and derivatives
Following early partial redemption of £1.0 million of convertible loan notes
in September 2025, a total of £18.2 million notes remain outstanding, which
are recorded as £15.9 million on an amortised cost basis in the Consolidated
Statement of Financial Position at 31 October 2025 (30 April 2025: amortised
cost basis of £15.8 million).
These notes are due to be repaid in August 2027 (£1.75 million) and November
2027 (£16.45 million) unless converted by Redmile LLC into ordinary Scancell
shares.
Derivative liabilities at 31 October 2025 associated with the above notes
totalling £4.4 million (30 April 2025: £7.5 million) represented the fair
value of the conversion feature of the convertible loan notes at the
respective period ends. The non-cash decrease in liabilities reflected
reductions in Scancell's share price, share price volatility, the number of
shares convertible following the early partial redemption, and in the time to
maturity of the outstanding notes.
The prior six-month period to 31 October 2024 also included a net gain of
£1.8 million on substantial modification of the convertible loan notes in
July 2024.
4 Taxation
Taxation for the 6 months ended 31 October 2025 is based on the effective
rates of taxation expected to apply for the year ended 30 April 2026.
R&D tax credits of £3.0 million relating to the year ended 30 April 2025
were subsequently received in December 2025.
5 Share options
The share-based payment expense for the six months ended 31 October 2025 was
£1.1 million (six months ended 31 October 2024: £0.5 million). The expense
was higher in the six-month period to 31 October 2025 following option awards
to directors in February 2025.
At 31 October 2025, a total of 99,053,255 options were outstanding (30 April
2025: 100,515,572 options).
6 Interim Results
These results were approved by the Board of Directors on 28 January 2026.
Copies of the interim report are available to the public from the Group's
registered office and the Group's website, www.scancell.co.uk
(http://www.scancell.co.uk) .
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact
rns@lseg.com (mailto:rns@lseg.com)
or visit
www.rns.com (http://www.rns.com/)
.
RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our
Privacy Policy (https://www.lseg.com/privacy-and-cookie-policy)
. END IR SEAFWAEMSEIF
Copyright 2019 Regulatory News Service, all rights reservedRecent news on Scancell Holdings
See all newsREG - Scancell Holdings - Half-year Financial Report
AnnouncementREG - Scancell Holdings - FDA clearance of IND application for iSCIB1+
AnnouncementREG - Scancell Holdings - Notice of Results
AnnouncementREG - Scancell Holdings - Continued improvement in PFS with iSCIB1+
AnnouncementREG - Scancell Holdings - Research Update
Announcement