** Shares of drug developer SGTX.O rise 3.6% to $6.13
** Sigilon Therapeutics says U.K regulators accepted its
application to start a clinical trial of its experimental
therapy, SIG-005, for Mucopolysaccharidosis Type I (MPS-1)
urn:newsml:reuters.com:*:nGNX9qzP8l
** MPS-1 is a progressive disorder caused by a genetic
mutation which affects several parts of the body
** Co says, with the approval, it remains on track to
initiate its early-to-mid stage study in the UK in the second
half of this year
** Says it has also submitted a clinical trial application
for the therapy in Brazil and plans to submit a similar
application with the U.S. FDA
** Stock has plunged 87.2% YTD
(Reporting by Amruta Khandekar)
((Amruta.Khandekar@thomsonreuters.com;))