(Updates)
** Shares of drug developer Sionna Therapeutics SION.O set
to open 50% above their offer price in their Nasdaq debut
** Stock indicated to open at $27 vs $18 IPO price
** SION sold ~10.6 mln shares, 20% more than initially
offered, at the top end of its marketed range of $16 to $18
apiece to raise $190.6 mln
** At the IPO price, the Waltham, Massachusetts-based firm
fetched a valuation of $765.4 mln
** Founded in 2019 and previously known as Sling
Therapeutics, SION is developing drugs to treat cystic fibrosis
** SION is vying for a slice of the cystic fibrosis market
that is dominated by drugmaker Vertex Pharmaceuticals VRTX.O
** Vertex booked almost $10 billion in sales in 2023 and has
significantly impacted cystic fibrosis treatment
** SION is evaluating its experimental drug candidates
SION-719 and SION-451 in early-stage trials in Australia
** Prior to the IPO, SION had raised about $330 mln from
investors, including RA Capital, TPG's Rise Fund, and Atlas
Venture
** Goldman Sachs, TD Cowen, Stifel and Guggenheim Securities
were the underwriters
(Reporting by Arasu Kannagi Basil in Bengaluru)
((ArasuKannagi.Basil@thomsonreuters.com;))