Graft Polymer (UK) - Commercial Collaboration Progress Update

Solvonis Therapeutics

28/08/2024 07:00

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RNS Number : 8682B  Graft Polymer (UK) PLC  28 August 2024

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28 August 2024

Graft Polymer (UK) Plc

(the "Company")

 

Substantial progress in Awakn collaboration

 

Identification of lead series, selection of Charnwood Discovery as synthesis
partner, and new patent filing

 

 

Graft Polymer (UK) Plc (LON: GPL), an innovative healthcare services company,
is pleased to report substantial progress in its collaboration with Awakn Life
Sciences Corp. (CSE: "AWKN", OTCQB: AWKNF) ("Awakn"), details of which were
announced on 18 July 2024.

 

The collaboration focuses on developing a new class of therapeutics for the
potential treatment of trauma-related mental health disorders, such as
Post-Traumatic Stress Disorder ("PTSD"), which affects approximately 13
million adults in the U.S. and 20 million collectively in the US and other key
international markets.

 

Recent progress includes:

 

·      Lead chemical series identified: Awakn has successfully
identified two aminoindane chemical series as co-leads for further
development. These series represent a promising new class of compounds with
the potential to improve treatment options for trauma-related mental health
disorders such as PTSD. The selection of these lead candidates is a pivotal
step in the drug development process.

 

·      Synthesis pathways defined: Awakn has also successfully
established synthesis pathways for these compounds. This achievement is
crucial, as it enables efficient and scalable production of the drug
candidates, which will be essential as the collaboration moves towards more
advanced pharmacological testing.

 

·      Charnwood Discovery selected as synthesis partner: Awakn has
selected Charnwood Discovery, a respected UK-based provider of drug discovery
services, as its synthesis partner. The selection of Charnwood Discovery,
known for its technical expertise, ensures that the synthesis process will be
conducted to a high standard.

 

·      New provisional patent filed: On 27 August 2024, Awakn filed a
provisional patent application with the US Patent and Trademark Office,
covering a new class of aminoindane chemical entities and their derivatives.
This provisional patent has been incorporated into the scope of the commercial
collaboration agreement between the Company and Awakn. This filing strengthens
the intellectual property portfolio underpinning the Graft Polymer-Awakn
collaboration, further reinforcing the Company's competitive edge in the
biopharmaceutical market.

 

 

Anthony Tennyson, CEO, Graft Polymer (UK) Plc, commented:

"We are thrilled with the progress made in our collaboration with Awakn. The
identification of the lead chemical series and the filing of a new patent
significantly advance our goal of developing transformative therapies for
trauma-related mental health disorders such as PTSD.

 

"These developments not only validate the scientific strength of the
partnership but also position us well for the next stages of development. The
addition of Charnwood Discovery as our synthesis partner further ensures that
we are on the right path towards bringing these promising compounds to
market."

 

 

Enquiries:

Graft Polymer (UK) Plc

Anthony Tennyson, CEO and Executive Director.
anthonytennyson@graftpolymer.co.uk

 

Allenby Capital (Broker) +44 (0) 20 3328 5656

Nick Naylor / Liz Kirchner (Corporate Finance) | Guy McDougall (Sales)

 

 

About Graft Polymer (UK) Plc

 

Graft Polymer (UK) Plc is an innovative healthcare services company dedicated
to helping biopharmaceutical companies specializing in central nervous system
disorders enhance the effectiveness of their therapeutics.

 

For more information, please visit www.graftpolymer.co.uk.

 

About Awakn Life Sciences Corp.

 

Awakn Life Sciences Corp. is a clinical-stage biotechnology company developing
therapeutics for substance use and mental health disorders. Awakn's near-term
focus is on Alcohol Use Disorder, a condition affecting approximately 29
million adults in the US and approximately 40 million in international
markets. Awakn's goal is to provide therapeutics to addiction sufferers;
commercialising Awakn's R&D pipeline across multiple channels.

 

For more information, please visit awaknlifesciences.com

 

 

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