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SWTX — SpringWorks Therapeutics News Story

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U.S. stocks were poised to open lower on Tuesday after a strong run of gains in
November as investors remained cautious ahead of Federal Reserve officials'
comments that could offer some clues on the interest rate path.  .N 
    
    At 9:06 ET, Dow e-minis  1YMc1  were down 0.05% at 35,356. S&P 500 e-minis
 ESc1  were down 0.18% at 4,552.75, while Nasdaq 100 e-minis  NQc1  were down
0.21% at 15,975.5.
 
 The top two NYSE percentage gainers premarket  .PRPG.NQ :
 ** UpHealth  UPH.N , up 9.1%
 ** Clearway Energy  CWEN.N , up 8.0%
 
 The top three NYSE percentage losers premarket  .PRPL.NQ :
 ** Oil States International  OIS.N , down 26.9%
 ** Xponential Fitness  XPOF.N , down 8.5%
 ** Cool Company  CLCO.N , down 7.7%
 
 The top Nasdaq percentage gainer premarket  .PRPG.O :
 ** Icecure Medical  ICCM.O , up 54.7%
 
 The top two Nasdaq percentage losers premarket  .PRPL.O :
 ** Tharimmune  THAR.O , down 69.5%
 ** SenesTech  SNES.O , down 39.9%
 
 
 ** SpringWorks Therapeutics  SWTX.O : up 9.4% premarket
 BUZZ - Gains after FDA approves non-cancerous tumors treatment for adults
 urn:newsml:reuters.com:*:nL4N3CT27S 
    
 ** Boeing  BA.N : up 1.7% premarket
 BUZZ - Rises after RBC upgrades to 'outperform,' sets PT at Street-high
 urn:newsml:reuters.com:*:nL4N3CT27Y 

 ** Affirm Holdings  AFRM.O : up 2.4% premarket
 BUZZ - Rises as Jefferies upgrades to 'hold'  urn:newsml:reuters.com:*:nL4N3CT26O 
    
 ** PDD Holdings  PDD.O : up 14.9% premarket
 BUZZ - Up on Q3 revenue beat  urn:newsml:reuters.com:*:nL4N3CT2HI 
    
 ** Zscaler  ZS.O : down 5.5% premarket
 BUZZ - Slides after lower-than-expected billings  urn:newsml:reuters.com:*:nL4N3CT2JH 
    
 ** Carlyle Group  CG.O : up 6.2% premarket
 BUZZ - Jumps on S&P MidCap inclusion  urn:newsml:reuters.com:*:nL1N3CT0VD 
    
 ** Cool Company  CLCO.N : down 7.7% premarket
 BUZZ - Drops after lower-than-expected Q3 revenue  urn:newsml:reuters.com:*:nL4N3CT2MC 
 ** Newmont Corp  NEM.N : up 0.6% premarket   
 ** Barrick Gold  GOLD.N : up 0.5% premarket
 ** AngloGold Ashanti  AU.N : up 1.9% premarket
 ** Harmony Gold Mining  HMY.N : up 2.2% premarket
 BUZZ - Gold miners climb as bullion steadies near six-month high  urn:newsml:reuters.com:*:nL4N3CT2OU 
    
 ** Novavax  NVAX.O : up 1.9% premarket
 BUZZ - Rises as WHO clears use of updated COVID shot  urn:newsml:reuters.com:*:nL4N3CT2QA 
    
 ** Adobe  ADBE.O : down 0.5% premarket
 BUZZ - Dips as UK regulator raises concern over $20 bln Figma deal  urn:newsml:reuters.com:*:nL4N3CT2S3
    
 ** Estee Lauder Companies  EL.N : up 1.0% premarket
 BUZZ - Rises as HSBC starts coverage with 'buy' rating  urn:newsml:reuters.com:*:nL4N3CT2WL 
    
 ** Emergent Biosolutions  EBS.N : up 6.8% premarket
 BUZZ - Rises on BARDA contract to procure anthrax vaccine  urn:newsml:reuters.com:*:nL4N3CT2X6 
    
 ** Welltower  WELL.N : down 1.1% premarket
 BUZZ - Falls on RBC downgrade to 'sector perform'  urn:newsml:reuters.com:*:nL4N3CT2Z0X 
    
 ** Avidity Biosciences  RNA.O : up 26.6% premarket
 BUZZ - Soars on licensing, research deal with Bristol Myers  urn:newsml:reuters.com:*:nL4N3CT2ZD 
    
 ** Lexeo Therapeutics  LXEO.O : up 7.3% premarket
 BUZZ - Rises as IPO research quiet period ends  urn:newsml:reuters.com:*:nL4N3CT2ZE 

 (Compiled by Anuja Bharat Mistry and Rajarshi Roy)
 ((AnujaBharat.Mistry@thomsonreuters.com))

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