** Shares of drugmaker Supernus Pharmaceuticals SUPN.O
fall ~22% to $31 premarket
** On late Tuesday, co said its depression drug, SPN-820,
did not meet main goal of reduction in depressive symptoms in a
mid-stage trial
** Trial tested 250 patients with treatment-resistant
depression and found no statistically significant change
compared to a placebo
** Trial used Montgomery-Asberg Depression Rating Scale to
measure severity of depression symptoms such as sadness, inner
tension, sleep reduction and inability to feel
** SUPN gained 30.4% in 2024
(Reporting by Kamal Choudhury in Bengaluru)
((Kamal.Choudhury@thomsonreuters.com;))