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REG-Syncona Limited: Interim Results <Origin Href="QuoteRef">SYNCS.L</Origin> - Part 2

- Part 2: For the preceding part double click  ID:nPRrM58D0a 

    
 Investment in Subsidiaries ((1))                                                                                                                                       403        - 
 Total Investment in Subsidiaries                                                                                                                                       403        - 
                                                                                                                                                                                     
 Other Net Assets                                                                                                                                                                    
 Cash and cash equivalents ((4))                                                                                                                                     36,119      3.5 
 Charitable donations                                                                                                                                               (2,376)    (0.2) 
 Other assets and liabilities                                                                                                                                       (9,157)    (0.9) 
 Total Other Net Assets                                                                                                                                              24,586      2.4 
                                                                                                                                                                                     
 Total Net Asset Value                                                                                                                                            1,032,173    100.0 
 of the Group                                                                                                                                                                        

((1)) The fair value of Syncona Holdings Limited amounting to £433,463,002 is
comprised of investments in life science companies of £431,124,622 and
investment in SIML of £402,849, other net assets of £1,239,032 in Syncona
Portfolio Limited and other net assets of £696,499 in Syncona Holdings
Limited.

((2)) The fair value of the investment in Syncona Investments LP Incorporated
amounting to £600,460,237 is comprised of the investment in the funds
portfolio of £552,006,502 (including the open forward currency contracts of
£3,979,499), the investment in the CRT Pioneer Fund of £24,052,234, cash of
£24,470,000 and other net liabilities of £68,499. The CRT Pioneer Fund is
64.1 per cent owned by the Group; however the Group has no control over the
fund.

((3)) The life science portfolio of £455,176,856 consists of life science
investments totalling £431,124,622 held by Syncona Holdings Limited and the
CRT Pioneer Fund of £24,052,234 held by Syncona Investments LP Incorporated.

((4)) Total cash held by the Group is £36,119,379. Of this amount £315,852
is held by Syncona Limited, and £24,470,000 and £11,333,527 is held by
Syncona Investments LP Incorporated and Syncona Portfolio Limited
respectively. Cash held by Syncona Investments LP Incorporated and Syncona
Portfolio Limited is not shown in Syncona Limited’s Consolidated Statement
of Financial Position.

See note 5 for a description of Syncona Holdings Limited and Syncona
Investments LP.

CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME

For the period ended 30 September 2017

                                                                                                                                                           
                                                                                                             Unaudited six     Unaudited six       Audited 
                                                                                                              months to 30      months to 30    year to 31 
                                                                                                            September 2017    September 2016    March 2017 
                                                                            Notes     Revenue    Capital             Total             Total         Total 
                                                                                        £'000      £'000             £'000             £'000         £'000 
                                                                                                                                                           
 Investment income                                                                                                                                         
 Other income                                                                          21,118          -            21,118            10,183        14,561 
 Total investment income                                                               21,118          -            21,118            10,183        14,561 
                                                                                                                                                           
 Net gains on financial assets at fair value through profit or loss           6             -    137,281           137,281            13,571        71,375 
 Total gains                                                                                -    137,281           137,281            13,571        71,375 
                                                                                                                                                           
 Expenses                                                                                                                                                  
 Charitable donation                                                          7         2,376          -             2,376             2,381         4,752 
 Management fees                                                                        5,438          -             5,438               449         2,774 
 General expenses                                                                       1,269          -             1,269               424         1,119 
 Total expenses                                                                         9,083          -             9,083             3,254         8,645 
                                                                                                                                                           
 Profit for the period/year                                                            12,035    137,281           149,316            20,500        77,291 
                                                                                                                                                           
 Earnings per Ordinary Share                                                  10        1.83p     20.84p            22.67p             5.32p        16.72p 
 Diluted earnings per Ordinary Share                                          10        1.81p     20.66p            22.47p             5.32p        16.72p 

The total columns of this statement represent the Group’s Consolidated
Statement of Comprehensive Income, prepared in accordance with International
Financial Reporting Standards as adopted by the European Union and
interpretations adopted by the International Accounting Standards Board.
Whilst the Company is not a member of the Association of Investment Companies
(the “AIC”), the supplementary revenue and capital columns are both
prepared under guidance published by the AIC.

The profit for the period is equivalent to the “total comprehensive
income” as defined by IAS 1 Presentation of Financial Statements (‘IAS
1’). There is no other comprehensive income as defined by IFRS.

All the items in the above statement derive from continuing operations.

CONSOLIDATED STATEMENT OF FINANCIAL POSITION

As at 30 September 2017

                                                                                  Unaudited             Unaudited              Audited 
                                                                               30 September          30 September             31 March 
                                                                                       2017                  2016                 2017 
                                                                     Notes            £'000   £'000                 £'000 
                                                                                                                                       
 ASSETS                                                                                                                                
 Non-current assets                                                                                                                    
 Financial assets at fair value through profit or loss                 8          1,033,923               485,865              896,469 
                                                                                                                                       
 Current assets                                                                                                                        
 Bank and cash deposits                                                                 316                   320                  105 
 Trade and other receivables                                                          3,025                 2,485                4,772 
 Total assets                                                                     1,037,264               488,670              901,346 
                                                                                                                                       
 LIABILITIES AND EQUITY                                                                                                                
 Non-current liabilities                                                                                                               
 Share based payment                                                   9              1,083                     -                   46 
                                                                                                                                       
 Current liabilities                                                                                                                   
 Share based payment                                                   9                710                     -                    - 
 Payables                                                                             3,298                 2,587                6,062 
 Total liabilities                                                                    5,091                 2,587                6,108 
                                                                                                                                       
 EQUITY                                                                                                                                
 Share capital account                                                 10           763,016               408,009              760,327 
 Distributable capital reserves                                                     269,157                78,074              134,911 
 Total equity                                                                     1,032,173               486,083              895,238 
                                                                                                                                       
 Total liabilities and equity                                                     1,037,264               488,670              901,346 
                                                                                                                                       
 Total net assets attributable to holders of Ordinary Shares                                                                           
                                                                                  1,032,173               486,083              895,238 
                                                                                                                                       
 Number of Ordinary Shares in Issue                                    10       659,952,090           386,138,785          658,387,407 
                                                                                                                                       
                                                                                                                          
 Net assets attributable to holders ofOrdinary Shares (per share)      10             £1.56                 £1.26                £1.36 

The unaudited Consolidated Financial Statements were approved on 22
November 2017.

CONSOLIDATED STATEMENT OF CHANGES IN NET ASSETS ATTRIBUTABLE TO HOLDERS OF
ORDINARY SHARES

                                                           Share                                      
                                                         capital     Capital     Revenue              
                                                         account    reserves    reserves        Total 
                                                 Notes     £'000       £'000       £'000        £'000 
                                                                                                      
 As at 31 March 2016 (audited)                           406,208      66,037           -      472,245 
                                                                                                      
 Total comprehensive income                                                                           
 for the period                                                -      13,571       6,929       20,500 
 Transactions with shareholders:                                                                      
 Distributions                                                 -     (1,534)     (6,929)      (8,463) 
 Scrip dividend shares issued during the period            1,801           -           -        1,801 
 As at 30 September 2016 (unaudited)                     408,009      78,074           -      486,083 
                                                                                                      
 Total comprehensive income                                                                           
 for the period                                                -      57,804     (1,013)       56,791 
 Transactions with shareholders:                                                                      
 Distributions                                                 -       (967)         967            - 
 Issuance of shares                                      357,054           -           -      357,054 
 Share issue costs                                       (4,736)           -           -      (4,736) 
 Share based payment                               9           -           -          46           46 
 As at 31 March 2017 (audited)                           760,327     134,911           -      895,238 
                                                                                                      
 Total comprehensive income                                                                           
 for the period                                                -     137,281      12,035      149,316 
 Transactions with shareholders:                                                                      
 Distributions                                     11          -     (3,035)    (12,108)     (15,143) 
 Scrip dividend shares issued during the period    10      2,689           -           -        2,689 
 Share based payment                               9           -           -          73           73 
 As at 30 September 2017 (unaudited)                     763,016     269,157           -    1,032,173 

CONSOLIDATED STATEMENT OF CASH FLOWS

For the period ended 30 September 2017

                                                                                                         Unaudited six                   Unaudited six       Audited 
                                                                                                          months to 30                    months to 30    year to 31 
                                                                                                             September                       September         March 
                                                                                                                  2017                            2016          2017 
                                                                         Notes                                   £'000                           £'000         £'000 
                                                                                                                                                                     
 Cash flows from operating activities                                                                                                                                
 Profit for the period/year                                                                                    149,316                          20,500        77,291 
 Adjusted for:                                                                                                                                                       
 Gains on financial assets at fair value through profit or loss            6                                 (137,281)                        (13,571)      (71,375) 
 Operating cash flows before movements in working capital                                                       12,035                           6,929         5,916 
 Decrease in other receivables                                                                                   1,747                           2,310            23 
 (Decrease)/increase in other payables                                                                         (1,017)                         (2,298)         1,177 
 Net cash generated from operating activities                                                                   12,765                           6,941         7,116 
                                                                                                                                                                     
 Cash flows from investing activities                                                                                                                                
 Purchase of financial assets at fair value through profit or loss                                            (90,385)                               -     (169,235) 
 Return of capital contribution                                                                                 90,285                               -         4,000 
 Net cash used in investing activities                                                                           (100)                               -     (165,235) 
                                                                                                                                                                     
 Cash flows from financing activities                                                                                                                                
 Issuance of shares                                                                                                  -                               -       169,581 
 Share issue costs                                                                                                   -                               -       (4,736) 
 Distributions                                                             11                                 (12,454)                         (6,662)       (6,662) 
 Net cash (used in)/generated from financing activities                                                       (12,454)                         (6,662)       158,183 
                                                                                                                                                                     
 Net increase in cash and cash equivalents                                                                         211                             279            64 
 Cash and cash equivalents at beginning of period/year                                                             105                              41            41 
 Cash and cash equivalents at end of period/year                                                                   316                             320           105 
                                                                                                                                                                     
 Supplemental disclosure of non-cash investing and financing activities:                                                                                             
                                                                                                                                                                     
 Investments purchased by issue of shares                                  8                                         -                               -     (187,473) 
 Issue of shares                                                           10                                    2,689                           1,801       189,274 
 Scrip dividend shares issued during the period/year                       10                                  (2,689)                         (1,801)       (1,801) 
 Net non-cash investing and financing activities                                                                     -                               -             - 

Cash held by the Company and its wholly owned subsidiaries (“Syncona Group
Companies”) is disclosed in the portfolio statement.

CONDENSED NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS

For the period ended 30 September 2017

1. GENERAL INFORMATION

Syncona Limited (the “Company”) is incorporated in Guernsey as a
registered closed-ended investment company. The Company’s Ordinary Shares
were listed on the premium segment of the London Stock Exchange (“LSE”) on
26 October 2012 when it commenced its business.

In December 2016, shareholders approved the expansion of the Company’s
investment policy and the acquisition from the Wellcome Trust of Syncona
Partners LLP, a portfolio of life science investments, together with its
investment management team (“the December 2016 transaction”). As part of
the transaction, the Company also acquired Cancer Research UK’s partnership
interest in the Cancer Research Technologies Pioneer Fund LP (“CRT Pioneer
Fund”).

2. ACCOUNTING POLICIES

The accounting policies applied in these interim results are the same as those
applied by the Group in its Annual Report and Accounts for the year ended
March 2017 and shall form the basis of the 2018 Annual Report and Accounts. No
new standards that have become effective in the period have had a material
effect on the Group’s financial statements.

Basis of preparation

The condensed consolidated financial statements have been prepared in
accordance with IAS 34 ‘Interim Financial Reporting’ and should be read in
conjunction with the Annual Report and Accounts for the year ended March 2017,
which have been prepared in accordance with International Financial Reporting
Standards (“IFRS”) as adopted by the European Union. The financial
information in these interim accounts was approved by the Board and authorised
for issue on 22 November 2017. The financial information is unaudited but has
been subject to a review by the Group’s independent auditor.

The condensed consolidated financial statements have been prepared under the
historical cost basis, except for investments and derivatives held at fair
value through profit or loss, which have been measured at fair value.

Going concern

The financial statements are prepared on a going concern basis. The Group’s
assets predominantly consist of securities and cash, amounting to £1,037.3
million (September 2016: £488.7 million; March 2017: £901.3 million) of
which 33.0 per cent (September 2016: 53.8 per cent; March 2017: 43.1 per cent)
are readily realisable within three months in normal market conditions. The
Group has liabilities including uncalled commitments to underlying investments
and funds amounting to £91.3 million (September 2016: £47.3 million; March
2017: £114.1 million). Accordingly, the Group has adequate financial
resources to continue in operational existence for 12 months following the
approval of the financial statements.

Basis of consolidation

All intra-group transactions, balances and expenses are eliminated on
consolidation. Entities that meet the definition of an Investment Entity under
IFRS 10 ‘Consolidated Financial Statements’ are held at fair value through
profit or loss in accordance with IAS 39 ‘Financial Instruments: Recognition
and Measurement’. Syncona Investments LP Incorporated (the
“Partnership”) and Syncona Holdings Limited (the “Holding Company”)
both meet the definition of Investment Entities. Syncona GP Limited (the
“General Partner”) is consolidated in full.

3. SIGNIFICANT ACCOUNTING JUDGEMENTS, ESTIMATES AND ASSUMPTIONS

The preparation of the interim results requires management to make judgements,
estimates and assumptions that affect the application of accounting policies
and the reported amounts of assets, liabilities, income and expenses.
Estimates and judgements are continually evaluated and are based on historical
experience and other factors, such as expectations of future events, and are
believed to be reasonable under the circumstances. Actual results may differ
from these estimates.

In preparing these interim results, the significant judgements made by
management in applying the Group’s accounting policies and the key sources
of estimation uncertainty were the same as those applied to the Annual Report
and Accounts for the year ended March 2017.

4. OPERATING SEGMENTS

The Group is made up of two main components, the ‘life science portfolio’
and the ‘funds portfolio’. The Board has considered the requirements of
IFRS 8 ‘Operating Segments’, and is of the view that the Group’s
activities form two segments under the standard, the ‘life science
portfolio’ and the ‘funds portfolio’. The life science portfolio and the
funds portfolio are managed on a global basis and, accordingly, no
geographical disclosures are provided.

The Board, as a whole, has been determined as constituting the chief decision
maker of the Group. The key measure of performance used by the Board to assess
the Group’s performance and to allocate resources is the total return based
on the Net Asset Value (“NAV”) per share, as calculated under IFRS.

Life science portfolio

The underlying investments in this segment are those whose activities focus on
developing products to deliver transformational treatments to patients.

Details of the underlying assets are shown in the Portfolio Statement.

Funds portfolio

The underlying assets in this segment are investments in a diversified
portfolio of hedge, equity and long-term alternative investment funds across
multiple asset classes.

Details of the underlying assets are shown in the Portfolio Statement.

Information about Reporting Segments

The following provides detailed information for the Group’s two reportable
segments for the six months to 30 September 2017, the six months to 30
September 2016 and the year to 31 March 2017:

 As at 30 September    Life Science Portfolio    Funds Portfolio    Unallocated (1)        Total 
 2017 (unaudited)                       £'000              £'000              £'000        £'000 
 Revenue                                    -                  -             21,118       21,118 
 Capital growth                       137,220                 61                  -      137,281 
 Expenses                                   -                  -            (9,083)      (9,083) 
 Net Assets                           455,177            552,007             24,989    1,032,173 
                                                                                                 
 As at 30 September    Life Science Portfolio    Funds Portfolio    Unallocated (1)        Total 
 2016 (unaudited)                       £'000              £'000              £'000        £'000 
 Revenue                                    -                  -             10,183       10,183 
 Capital growth                             -             13,571                  -       13,571 
 Expenses                                   -                  -            (3,254)      (3,254) 
 Net Assets                            10,631            460,800             14,652      486,083 
                                                                                                 
 As at 31 March 2017   Life Science Portfolio    Funds Portfolio    Unallocated (1)        Total 
 (audited)                              £'000              £'000              £'000        £'000 
 Revenue                                    -                  -             14,561       14,561 
 Capital growth                        24,801             46,574                  -       71,375 
 Expenses                                   -                  -            (8,645)      (8,645) 
 Net Assets                           226,554            582,808             85,876      895,238 

(1) Unallocated’ includes the dividends, donations and expenses for the
period, which are not relevant to allocate by segment. The revenue is
unrelated to either segment’s performance.

The net assets of each segment can be agreed to the Portfolio Statement. The
capital growth can be agreed to the Statement of Comprehensive Income.

Prior to the December 2016 transaction, the Group’s activities formed a
single segment, namely the funds portfolio. Following the December 2016
transaction, the reporting segments have changed so the 2016 segments have
been restated. The restatement relates to the CRT Pioneer Fund which was
previously treated as a Fund Investment and deemed immaterial for disclosure.
The CRT Pioneer Fund is included in the life science portfolio as the
underlying assets of this fund are also developing products to deliver
transformational treatments to patients.

5. INVESTMENT IN SUBSIDIARIES AND ASSOCIATES

The Company meets the definition of an Investment Entity in accordance with
IFRS10. Therefore, with the exception of the General Partner, the Company does
not consolidate its subsidiaries and indirect associates, but rather
recognises them as financial assets at fair value through profit or loss.

Directly owned subsidiaries

 Subsidiary                            Country of incorporation    Principal activity  % interest 
 Syncona GP Limited                                    Guernsey       General Partner        100% 
 Syncona Investments LP Incorporated                   Guernsey  Portfolio management        100% 
 Syncona Holdings Limited                              Guernsey  Portfolio management        100% 

There are no significant restrictions on the ability of subsidiaries to
transfer funds to the Company.

Indirect interests in subsidiaries

 Indirect subsidiaries                   Country of incorporation            Immediate parent    Principal activity  % interest (1) 
 Syncona Discovery Limited                                     UK  Syncona Investments LP Inc  Portfolio management            100% 
 Syncona Portfolio Limited                               Guernsey    Syncona Holdings Limited  Portfolio management            100% 
 Syncona IP Holdco Limited                                     UK   Syncona Portfolio Limited  Portfolio management            100% 
 Syncona Investment Management Limited                         UK    Syncona Holdings Limited  Portfolio management            100% 
 Syncona Partners LLP ²                                        UK    Syncona Holdings Limited  Portfolio management            100% 
 Syncona Management LLP²                                       UK    Syncona Holdings Limited  Portfolio management            100% 
 Syncona LLP²                                                  UK    Syncona Holdings Limited  Portfolio management            100% 
 Syncona Management Services Limited²                          UK      Syncona Management LLP  Portfolio management            100% 
 Blue Earth Diagnostics Limited                                UK   Syncona Portfolio Limited       Medical imaging             90% 
 Freeline Therapeutics Limited                                 UK   Syncona Portfolio Limited          Gene therapy             83% 
 Gyroscope Therapeutics Limited                                UK   Syncona Portfolio Limited          Gene therapy             74% 
 Achilles Therapeutics Limited                                 UK   Syncona Portfolio Limited         Immunotherapy             65% 
                                                                                                                                    
 Indirect associates                     Country of incorporation            Immediate parent    Principal activity  % interest (1) 
 Nightstar Therapeutics plc                                    UK   Syncona Portfolio Limited          Gene therapy             42% 
 Autolus Limited                                               UK   Syncona Portfolio Limited      T-Cell Therapies             41% 
 Cambridge Epigenetix Limited                                  UK   Syncona Portfolio Limited        Research tools             14% 

(1) Based on undiluted issued share capital.

² Entities in members voluntary liquidation.

6. NET GAINS ON FINANCIAL ASSETS AT FAIR VALUE THROUGH PROFIT OR LOSS

The net gains on financial assets at fair value through profit or loss arise
from the Group’s holdings in the Partnership and Holding Company.

                                                                               Unaudited six     Unaudited six       Audited 
                                                                                months to 30      months to 30    year to 31 
                                                                              September 2017    September 2016    March 2017 
                                                                                       £'000             £'000         £'000 
 Net gains from: Syncona Investments LP Incorporated                    6.a               61            13,571        46,574 
 Syncona Holdings Limited                                               6.b          137,220                 -        24,801 
                                                                                     137,281            13,571        71,375 

6.a Movements in Syncona Investments LP Incorporated:

                                                                                                                                Unaudited six     Unaudited six       Audited 
                                                                                                                                 months to 30      months to 30    year to 31 
                                                                                                                               September 2017    September 2016    March 2017 
                                                                                                                                        £'000             £'000         £'000 
 Investment income                                                                                                                        877               498         1,333 
 Rebates and donations                                                                                                                    901               914         2,035 
 Expenses                                                                                                                               (118)             (165)         (303) 
 Distributions                                                                                                                       (21,118)          (10,183)      (14,561) 
 Realised gains on financial assets at fair value through profit or loss                                                               18,734               995         7,324 
 Movement in unrealised (losses)/gains on financial assets at fair value through profit or loss                                       (7,361)            39,539        72,143 
 Gains/(losses) on forward currency contracts                                                                                           9,103          (18,477)      (23,368) 
 (Losses)/gains on foreign currency                                                                                                     (957)               450         1,971 
 Net gains on financial assets at fair value through profit or loss                                                                        61            13,571        46,574 
                                                                                                                                                                              

6.b Movements in Syncona Holdings Limited:

                                                                                                                                   Audited period 
                                                                                                                  Unaudited six           from 24 
                                                                                                                   months to 30     November 2016 
                                                                                                                      September       to 31 March 
                                                                                                                           2017              2017 
                                                                                                                          £'000             £'000 
                                                                                                                                                  
 Residual income from liquidated subsidiaries                                                                               726                 - 
 Expenses                                                                                                                  (17)              (36) 
 Movement in unrealised gains on life science investments at fair value through profit or loss                          136,844            24,940 
 Movement in unrealised losses on wholly owned Group companies at fair value through profit or loss                       (333)             (103) 
 Net gains on financial assets at fair value through profit or loss                                                     137,220            24,801 

7. CHARITABLE DONATIONS

As part of the December 2016 transaction, the Company has an obligation to
make a donation to charity, paid in arrears, of 0.3 per cent of the total NAV
of the Company during the financial year calculated on a monthly basis. For
the years ending March 2017 and March 2018 the Company has agreed that the
charitable donations will not be less than £4,751,608. Any amount paid in
excess of 0.3 per cent of the total NAV of the Company in those years will be
recovered by reducing the charitable donations in subsequent years if the NAV
of the Company rises above £1,583,869,333. Half of the donation is donated to
The Institute of Cancer Research (“ICR”) and the other half to The BACIT
Foundation. The BACIT Foundation grants those funds to charities proposed
annually by The BACIT Foundation, in proportions determined each year by
shareholders of the Company.

During the period, accrued charitable donations amounted to £2,375,804
(September 2016: £2,381,232, March 2017: £4,751,608). As at September 2017,
£2,375,804
(September 2016: £2,381,232, March 2017: £4,751,608) remained payable.

8. FINANCIAL ASSETS AT FAIR VALUE THROUGH PROFIT OR LOSS

                                                            Unaudited       Unaudited                  
                                                         30 September    30 September          Audited 
                                                                 2017            2016    31 March 2017 
                                                                £'000           £'000            £'000 
 Syncona Investments LP Incorporated               8.a        600,460         485,865          690,682 
 Syncona Holdings Limited                          8.b        433,463               -          205,787 
                                                            1,033,923         485,865          896,469 

The financial assets at fair value through profit or loss represent the
movement in the Group’s underlying investments during the period.

8.a The net assets of Syncona Investments LP Incorporated.

                                                                                                                                            Unaudited       Unaudited                  
                                                                                                                                         30 September    30 September          Audited 
                                                                                                                                                 2017            2016    31 March 2017 
                                                                                                                                                £'000           £'000            £'000 
 Cost of the Partnership's investments at the start of the period/year                                                                        460,046         388,412          388,412 
 Purchases during the period/year                                                                                                              67,049          11,020          136,197 
 Sales during the period/year                                                                                                               (101,462)        (27,077)         (60,804) 
 Return of capital                                                                                                                            (9,076)         (2,168)         (11,083) 
 Net realised gains on disposals during the period/year                                                                                        18,734             995            7,324 
 Cost of the Partnership's investments at the end of the period/year                                                                          435,291         371,182          460,046 
 Net unrealised gains on investments at the end of the period/year                                                                            136,788         111,545          144,149 
 Fair value of the Partnership's investments at the end of the period/year                                                                    572,079         482,727          604,195 
 Open forward currency contracts                                                                                                                3,979        (11,296)              437 
 Cash and cash equivalents                                                                                                                     24,470          16,567           86,204 
 Other net current liabilities                                                                                                                   (68)         (2,133)            (154) 
 Financial assets at fair value through profit or loss at the end of the period/year                                                          600,460         485,865          690,682 

8.b The net assets of Syncona Holdings Limited.

                                                                                                                               Unaudited                  
                                                                                                                            30 September          Audited 
                                                                                                                                    2017    31 March 2017 
                                                                                                                                   £'000            £'000 
 Cost of the Holding Company's investments at the start of the period/year                                                       180,479                - 
 Purchases during the period/year                                                                                                 90,940          180,479 
 Cost of the Holding Company's investments at the end of the period/year                                                         271,419          180,479 
 Net unrealised gains on investments at the end of the period/year                                                               161,348           24,837 
 Fair value of the Holding Company's investments at the end of the period/year                                                   432,767          205,316 
 Other net current assets                                                                                                            696              471 
 Financial assets at fair value through profit or loss at the end of the period/year                                             433,463          205,787 

9. LONG TERM INCENTIVE PLAN

                                                Unaudited six months to 30 September 2017    Unaudited six months to 30 September 2016    Audited year to 31 March 2017 
                                                                                    £'000                                        £'000                            £'000 
 Current share-based payments                                                         710                                            -                                - 
 Non-current share-based payments                                                   1,083                                            -                               46 
 Total share-based payments                                                         1,793                                            -                               46 

Share-based payments represent a liability associated with awards of
Management Equity Shares (“MES”) in the Holding Company, relevant details
of which are set out in note 2 of the Annual Report and Accounts for the year
ended March 2017. There were no MES in September 2016 therefore there is no
comparative information for that date. There were no share-based payments for
the Company’s shares during the period ended 30 September 2017 (March 2017:
nil and September 2016: nil). 

When a participant elects to realise vested MES by sale of the MES to the
Company, half of the proceeds (net of anticipated taxes) will be settled in
shares of the Company, with the balance settled in cash. During the period
ended 30 September 2017 the charge to the Consolidated Statement of
Comprehensive Income was £146,500 (March 2017: £92,000) of which £73,250
(March 2017: £46,000) is expected to be settled in shares and £73,250 (March
2017: £46,000) is expected to be settled in cash. In addition, the cash
liability was revalued incurring a charge of £1,673,486.

The fair value of the MES is established via external valuation as set out in
note 2 of the Annual Report and Accounts for the year ended March 2017. For
the awards of MES made in the period ended 30 September 2017, the applicable
hurdle value was 15 per cent (March 2017: 15 per cent) growth in the value of
the Holding Company above the value at the date of award. No further
performance targets apply to the MES awards. Each MES is entitled to share
equally in value attributable to the Holding Company above the applicable
hurdle value.

The fair value of awards made in the period ended 30 September 2017 was
£13,000 (March 2017: £648,000).

The following MES were held by participants:

 Date of award     MES awarded    MES vested at 30 September 2017    Holding Company hurdle                   Vesting period 
 December 2016      26,304,603                                  -            £203.4 million    December 2016 - December 2020 
 March 2017          1,480,721                                  -            £203.4 million          March 2017 - March 2021 
 July 2017             489,854                                  -            £208.0 million            July 2017 - July 2021 

Number of ordinary shares in the Holding Company in issue at 30 September
2017: 255,721,814 (March 2017: 176,986,208).

Value of the Holding Company at 30 September 2017 adjusted for MES purposes:
£429.0 million (March 2017: £200.1 million).

At 30 September 2017, if all MES were realised the number of shares issued in
the Company would be 5,095,588 (March 2017: 1,087,495).

The cash liability is revalued at the end of each accounting period. At 30
September 2017 the fair value of the cash liability was £1,792,736 (March
2017: nil). The revaluation of the cash liability is a charge to the Statement
of Comprehensive Income.

10. SHARE CAPITAL ACCOUNT

A. Authorised Share Capital

The Company is authorised to issue an unlimited number of shares, which may
have a par value or no par value. The shares can be issued as Ordinary Shares,
C Shares or other such classes and in any currency at the discretion of the
Board.

The Company is a closed-ended investment company with an unlimited life. The
Ordinary Shares are not puttable instruments because redemption is conditional
upon certain market conditions and/or Board approval. As such they are not
required to be classified as debt under IAS 32 – ‘Financial Instruments:
Disclosure and Presentation’.

As the Company’s Shares have no par value, the share price consists solely
of share premium and the amounts received for issued shares are recorded in
the Share Capital Account in accordance with The Companies (Guernsey) Law,
2008.

The Company also has the authority, subject to various terms as set out in its
Articles and in accordance with The Companies (Guernsey) Law, 2008, to acquire
up to 14.99 per cent of the Shares in issue. The Company intends to renew this
authority annually.

Ordinary Shares carry the right to receive all income of the Company
attributable to the Ordinary Shares of such class and to participate in any
distribution of such income made by the Company,
pro-rata to the relative calculated NAV of each of the classes of Ordinary
Shares and within each such class income shall be divided pari passu among the
holders of Ordinary Shares of that class in proportion to the number of
Ordinary Shares of such class held by them. 

The Founder Share issued at the date of incorporation was redesignated, by
special resolution dated 28 September 2012, as a Deferred Share and
transferred to The BACIT Foundation. This
non-participating non-redeemable Deferred Share has no other rights to assets
or dividends, except to payment of £1 on the liquidation of the Company and
carries a right to vote only if there are no other classes of voting share of
the Company in issue.

                                                                           Unaudited             Unaudited             Unaudited 
                                                                  Ordinary Shares at    Ordinary Shares at    Ordinary Shares at 
                                                                        30 September          30 September              31 March 
                                                                                2017                  2016                  2017 
                                                                               £'000                 £'000                 £'000 
 Ordinary Share Capital                                                                                                          
 Balance at the start of the period/year                                     760,327               406,208               406,208 
 Issued during the period/year                                                     -                     -               357,054 
 Scrip dividend shares issued during the period/year                           2,689                 1,801                 1,801 
 Share issue costs                                                                 -                     -               (4,736) 
 Balance at the end of the period/year                                       763,016               408,009               760,327 
                                                                                                                                 
                                                                           Unaudited             Unaudited             Unaudited 
                                                                  Ordinary Shares at    Ordinary Shares at    Ordinary Shares at 
                                                                        30 September          30 September              31 March 
                                                                                2017                  2016                  2017 
 Ordinary Share Capital                                                       Shares                Shares                Shares 
 Balance at the start of the period/year                                 658,387,407           384,665,158           384,665,158 
 Issued during the period/year                                                     -                     -           272,248,622 
 Scrip dividend shares issued during the period/year                       1,564,683             1,473,627             1,473,627 
 Balance at the end of the period/year                                   659,952,090           386,138,785           658,387,407 

A further £2,688,751 (1,564,683 Ordinary Shares) in new Ordinary Shares were
issued at a price of 171.84p as a result of the 2017 scrip dividend.

B. Capital reserves

Gains and losses recorded on the realisation of investments, realised exchange
differences, unrealised gains and losses recorded on the revaluation of
investments held at the period end and unrealised exchange differences of a
capital nature are transferred to capital reserves.

C. Earnings per Share

The calculations for the earnings per share attributable to the Ordinary
Shares of the Company are based on the following data:

                                                   Unaudited six months to 30 September 2017            Unaudited six   Audited year to 31 March 2017 
                                                                                               months to 30 September                                 
                                                                                                                  2016                                
 Earnings for the purposes of earnings per share                                £149,315,501               £20,499,938                    £77,291,393 
                                                                                                                                                      
 Basic weighted average number of shares                                         658,763,615               385,011,420                    462,399,882 
 Basic revenue earnings per share                                                      1.83p                     1.80p                          1.28p 
 Basic capital earnings per share                                                     20.84p                     3.52p                         15.44p 
 Basic earnings per share                                                             22.67p                     5.32p                         16.72p 
                                                                                                                                                      
 Diluted weighted average number of shares                                       664,471,801               385,011,420                    462,399,882 
 Diluted revenue earnings per share                                                    1.81p                     1.80p                          1.28p 
 Diluted capital earnings per share                                                   20.66p                     3.52p                         15.44p 
 Diluted earnings per share                                                           22.47p                     5.32p                         16.72p 

Earnings are diluted for the six months to September 2017 due to the MES
described in note 9.

 D. NAV per Share

                                                                                Unaudited            Unaudited    Audited year to 
                                                                        30 September 2017    30 September 2016      31 March 2017 
 Net assets for the purposes of NAV per share                              £1,032,172,609         £486,083,040       £895,238,499 
 Ordinary Shares in issue                                                     659,952,090          386,138,785        658,387,407 
 NAV per share                                                                    156.40p              125.88p            135.97p 
 Diluted NAV per share                                                            155.20p              125.88p            135.97p 

11. DISTRIBUTION TO SHAREHOLDERS

The Company may pay a dividend at the discretion of the Board. Following the
EGM in October 2013, each dividend paid by the Company will be in the form of
scrip as a default, with a cash dividend alternative, under which shareholders
may elect to receive cash in place of new Shares. Ordinary Shares issued
pursuant to a scrip dividend are issued at a price based on Ordinary Share
price.

During the period ended 30 September 2017, the Company declared and paid a
dividend of 2.3p per share amounting to £15,142,910 (September 2016:
£8,462,633) relating to the year ended March 2017 (March 2016). The dividend
was comprised of £12,454,159 cash (September 2016: £6,662,132) and a scrip
dividend of 

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