** Shares of Syros Pharmaceuticals Inc SYRS.O fall 84.5%
to 42 cents premarket
** Co on Tuesday said its drug, tamibarotene, did not meet
main goal of treating a high-risk form of a type of rare blood
cancer called myelodysplastic syndrome in a late-stage trial
** SYRS' trial failure leads to loan default with Oxford
Finance, co said
** Tamibarotene, when combined with azacitidine, showed a
complete response rate of 23.8% vs 18.8% for combination of
placebo and azacitidine, but data was not statistically
significant
** Azacitidine is used to treat certain types of blood
cancer, including myelodysplastic syndrome
** As of last close, stock has fallen ~65% YTD
(Reporting by Kamal Choudhury in Bengaluru)
((Kamal.Choudhury@thomsonreuters.com))