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SYRS Syros Pharmaceuticals News Story

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Wall Street's main indexes hit near-two month lows on Friday, after a profit
warning from global delivery bellwether FedEx spooked investors already worried
about aggressive rate hikes from the Federal Reserve tipping the economy into a
recession.  .N 
    
    At 11:37 a.m. ET, the Dow Jones Industrial Average  .DJI  was down 1.04% at
30,641.04. The S&P 500  .SPX  was down 1.30% at 3,850.75 and the Nasdaq
Composite  .IXIC  was down 1.65% at 11,361.524.
 
 The top three S&P 500  .PG.INX  percentage gainers:
 ** Newmont Corp  NEM.N , up 3%
 ** FirstEnergy Corp  FE.N , up 2%
 ** Lennar Corp  LEN.N , up 1.7%
 
 The top three S&P 500  .PL.INX  percentage losers:
 ** FedEx Corp  FDX.N , down 22.9%
 ** Packaging Corporation of America  PKG.N , down 11.8%
 ** WestRock Co  WRK.N , down 11%
 
 The top two NYSE  .PG.N  percentage gainers:
 ** Amprius Technologies Operating Inc  AMPX.N , up 51.2%
 ** Electromed Inc  ELMD.N , up 20.2%
 
 The top three NYSE  .PL.N  percentage losers:
 ** Getty Images Holdings Inc  GETY.N , down 25.6%
 ** FedEx Corp  FDX.N , down 22.9%
 ** NCR Corp  NCR.N , down 22.9%
 
 The top two Nasdaq  .PG.O  percentage gainers:
 ** Applied Optoelectronics Inc  AAOI.O , up 38.2%
 ** Alaunos Therapeutics Inc  TCRT.O , up 22.7%
 
 The top three Nasdaq  .PL.O  percentage losers:
 ** Aditxt Inc  ADTX.O , down 54.3%
 ** Nabriva Therapeutics Plc  NBRV.O , down 34.8%
 ** Scienjoy Holding Corp  SJ.O , down 34.3%
 
 
** FedEx Corp  FDX.N : down 22.9%
 BUZZ - Warning sends shudders through sector  urn:newsml:reuters.com:*:nL4N30N2U3
    
 
 ** Uber Technologies Inc  UBER.N : down 4.6%
 BUZZ - Shares down as co investigates cybersecurity incident after report of
breach  urn:newsml:reuters.com:*:nL4N30N24Y
    
 ** Applied Optoelectronics Inc  AAOI.O : up 38.2%
 BUZZ - Surges on sale of China facilities  urn:newsml:reuters.com:*:nL4N30N26K
    
 ** Syneos Health Inc  SYNH.O : down 3.1%
 BUZZ - Baird 'proactively' cuts PT on Syneos after bookings weakness
 urn:newsml:reuters.com:*:nL4N30N29N 
    
 ** Target Corp  TGT.N : down 0.5%
 ** Best Buy Co Inc  BBY.N : down 0.7%
 ** Amazon.com Inc  AZMN.O : down 3.2%
 ** Nike Inc  NKE.N : down 1.2%
 BUZZ - Shares of U.S. retailers wobble after FedEx warning  urn:newsml:reuters.com:*:nL4N30N29X 
    
 ** NCR Corp  NCR.N : down 22.9%
 BUZZ - Shares dive on plan to split into two companies  urn:newsml:reuters.com:*:nL4N30N29F 
    
 ** Shoals Technologies Group Inc  SHLS.O : up 0.6%
 BUZZ - Up after Cowen upgrades stock, hikes PT  urn:newsml:reuters.com:*:nL4N30N28U
    
 ** International Paper Co  IP.N : down 10.7%
 ** Packaging Corp of America  PKG.N : down 11.8%
 BUZZ - Containerboard glut an imminent threat to packaging firms - Jefferies
 urn:newsml:reuters.com:*:nL4N30N2DD
    
 ** B&G Foods Inc  BGS.N : down 3.0%
 ** Nomad Foods Ltd  NOMD.N : down 2.8%
 ** Vital Farms Inc  VITL.O : down 4.4%
 BUZZ - Jefferies cuts PT on some food companies over inflationary pressure
 urn:newsml:reuters.com:*:nL4N30N2BD
    
 ** Huntsman Corp  HUN.N : down 4.0%
 BUZZ - Slips on downbeat Q3 outlook  urn:newsml:reuters.com:*:nL4N30N2HX
    
 ** Spectrum Brands Holdings Inc  SPB.N : down 2.2%
 BUZZ - Receives setback with $4.3-bln deal in limbo - brokerage  urn:newsml:reuters.com:*:nL4N30N2I5
    
 ** Nordstrom Inc  JWN.N : up 2.0%
 BUZZ - Gains after Mexico's Liverpool takes near 10% stake  urn:newsml:reuters.com:*:nL4N30N2I7
    
 ** JetBlue Airways Corp  JBLU.O : down 2.2%
 BUZZ - Slips after flagging higher Q3 fuel cost  urn:newsml:reuters.com:*:nL4N30N2HZ
    
** Arrow Electronics Inc  ARW.N : down 4.1%
** Avnet Inc  AVT.O : down 5.5% 
 BUZZ - Wells Fargo bearish on Arrow, Avnet on slowing demand  urn:newsml:reuters.com:*:nL4N30N2K3
    
** SPAC Inflection Point Acquisition Corp  IPAX.O : up 1.3%
 BUZZ - Up on billion-dollar merger deal  urn:newsml:reuters.com:*:nL4N30N2LB
    
** CNB Financial Corp  CCNE.O : down 8.6%
 BUZZ - Falls on pricing share offering  urn:newsml:reuters.com:*:nL1N30N0WT
    
** Core & Main Inc  CNM.N : down 6.7%
 BUZZ - Slides as CD&R carves stake in secondary offering   urn:newsml:reuters.com:*:nL1N30N0ZP
    
 ** Alignment Healthcare Inc  ALHC.O : down 17.8%
 BUZZ - Drops on secondary stock deal  urn:newsml:reuters.com:*:nL1N30N11K
    
 ** Annexon Inc  ANNX.O : up 0.7%
 BUZZ - Jefferies starts Annexon Inc coverage with 'buy' rating  urn:newsml:reuters.com:*:nL4N30N2LH
    
 ** JanOne Inc  JAN.O : up 4.6%
 BUZZ - Rises on deal to buy Soin Therapeutics  urn:newsml:reuters.com:*:nL4N30N2S0
    
 ** Belite Bio Inc  BLTE.O : up 1.9%
 BUZZ - Gains on China nod for lead drug trial  urn:newsml:reuters.com:*:nL4N30N2M8
    
 ** General Electric Co  GE.N : down 4.9%
 BUZZ - Hits near-2-month low as supply chain hurdles threaten Q3  urn:newsml:reuters.com:*:nL4N30N2SJ

 ** NextDecade Corp  NEXT.O : down 10.7%
 ** New Fortress Energy Inc  NFE.O : down 4.9%    
 ** EQT Corp  EQT.N : down 4.7%
 ** Chesapeake Energy Corp  CHK.O : down 1.3%
 BUZZ - U.S. natural gas companies slump as futures dip over 4%  urn:newsml:reuters.com:*:nL4N30N2V1
    
 ** SVB Financial Group  SIVB.O : down 6.1%
 BUZZ - Slides as BofA cuts PT on murky outlook  urn:newsml:reuters.com:*:nL4N30N2U5
    
 ** Aditxt Inc  ADTX.O : down 54.3%
 BUZZ - Down on $20 mln stock offering  urn:newsml:reuters.com:*:nL4N30N2TQ
    
 ** FirstEnergy Corp  FE.N : up 2.0%
 BUZZ - CEO retires; shares up  urn:newsml:reuters.com:*:nL4N30N2VQ
    
 ** Waterdrop Inc  WDH.N : up 5.1%
 BUZZ - Morgan Stanley bullish on Waterdrop Inc on better fundamentals,
regulatory environment  urn:newsml:reuters.com:*:nL4N30N2PP

 ** JPMorgan Chase & Co  JPM.N : down 1.2%
 ** Wells Fargo & Co  WFC.N : down 1.0%
 ** Morgan Stanley  MS.N : down 1.7%
 ** Citigroup Inc  C.N : down 1.1%
 BUZZ - Big banks fall after FedEx warning spurs economic slowdown worries
 urn:newsml:reuters.com:*:nL4N30N2VF
    
 ** United Parcel Service Inc  UPS.N : down 4.5%
 ** Avis Budget Group Inc  CAR.O : down 6.7%  
 ** Southwest Airlines Co  LUV.N : down 4.7%
 ** CH Robinson Worldwide Inc  CHRW.O : down 2.7%  
 BUZZ - Dow transports slides as FedEx warning ripples  urn:newsml:reuters.com:*:nL1N30N1G2
 The 11 major S&P 500 sectors:

 Communication       .SPLRCL   down 1.20%
 Services                      
 Consumer            .SPLRCD   down 1.69%
 Discretionary                 
 Consumer Staples    .SPLRCS   down 0.20%
 Energy              .SPNY     down 2.02%
 Financial           .SPSY     down 1.21%
 Health              .SPXHC    down 0.63%
 Industrial          .SPLRCI   down 2.31%
 Information         .SPLRCT   down 1.46%
 Technology                    
 Materials           .SPLRCM   down 2.09%
 Real Estate         .SPLRCR   down 0.89%
 Utilities           .SPLRCU   down 0.09%
                

 (Compiled by Rajarshi Roy and Raghav Mahobe)
 ((Raghav.Mahobe@thomsonreuters.com))

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